{"id":"W2958262307","doi":"10.3892/mmr.2019.10498","title":"Identification of clinically relevant subgroups of COPD based on airway and circulating autoantibody profiles","year":2019,"lang":"en","type":"article","venue":"Molecular Medicine Reports","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"NIH Clinical Center; Canadian Institutes of Health Research; Higher Education Discipline Innovation Project; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Autoantibody; COPD; Exacerbation; Medicine; Immunology; Sputum; Internal medicine; Antibody; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004206504,0.0002880369,0.0005053646,0.001314604,0.0003056882,0.0006147012,0.000198892,0.000428857,0.0007149943],"category_scores_gemma":[0.001506716,0.0001025953,0.0003326652,0.0006502873,0.0002420835,0.0003967618,0.0004441125,0.0002440962,0.0001886127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001907306,"about_ca_system_score_gemma":0.0001945134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005598032,"about_ca_topic_score_gemma":0.0006818521,"domain_scores_codex":[0.9996916,0.00008622186,0.00003393535,0.00007750793,0.00005271511,0.00005804206],"domain_scores_gemma":[0.999396,0.0001648349,0.0002125442,0.00004675389,0.00006670426,0.0001131624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000572595,0.00008381793,0.9637594,0.0000529859,0.0001117376,0.000238953,0.0002703535,0.0004922576,0.02183184,0.0001710331,0.0001208906,0.01229415],"study_design_scores_gemma":[0.00001102365,0.0001688887,0.9952801,0.000007188829,0.00005264471,0.0005643826,0.0002197005,0.002251808,0.0008159972,0.0004227935,0.0001985525,0.000006914775],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986779,0.0002119939,0.0007104069,0.00002650898,0.000002663458,0.00002030408,0.00007912119,0.000008305905,0.0002627389],"genre_scores_gemma":[0.9989795,0.00006861001,0.0006363915,0.00001317548,0.000008826069,0.00001404958,0.0002141442,0.000002622947,0.00006263137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001314604,"threshold_uncertainty_score":0.002391875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122773328480126,"score_gpt":0.3141445515752936,"score_spread":0.3018672187272811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}