{"id":"W2958648554","doi":"10.1186/s40425-019-0662-5","title":"The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC)","year":2019,"lang":"en","type":"article","venue":"Journal for ImmunoTherapy of Cancer","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":738,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Center for Advancing Translational Sciences; University of Texas MD Anderson Cancer Center; National Institute for Health and Care Research; Cancer Research UK; Yale University; Society for Immunotherapy of Cancer; Università degli Studi di Milano; Brigham and Women's Hospital; Yale Cancer Center; Memorial Sloan-Kettering Cancer Center","keywords":"Pembrolizumab; Medicine; Nivolumab; Head and neck squamous-cell carcinoma; Oncology; Internal medicine; Immunotherapy; Cancer; Head and neck cancer; Population","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009401458,0.0004618526,0.001072432,0.00008809796,0.0004798929,0.00003376973,0.0004783328,0.0001758542,0.000130072],"category_scores_gemma":[0.00001428726,0.000227224,0.002375804,0.0002332727,0.0006357853,0.00005502466,0.00001478138,0.0001960715,1.292382e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005130998,"about_ca_system_score_gemma":0.0009539959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001583836,"about_ca_topic_score_gemma":0.0002342944,"domain_scores_codex":[0.9969221,0.00008680562,0.001571937,0.0003176359,0.0005697533,0.0005317052],"domain_scores_gemma":[0.9946727,0.001542063,0.002101972,0.0008543659,0.0007753607,0.00005356064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.100865,0.001232642,0.01176117,0.0006887403,0.006199082,2.346132e-7,0.006431517,0.0002965726,0.605678,0.0001525192,0.003766176,0.2629284],"study_design_scores_gemma":[0.0661817,0.01917744,0.04173076,0.0005986001,0.0005967335,0.00001309389,0.002135157,0.0004246919,0.4815457,0.0002950618,0.386924,0.0003771151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.790246,0.1989229,0.0001331381,0.003736073,0.001449216,0.004876777,0.0005977848,0.00000641737,0.00003172795],"genre_scores_gemma":[0.8873553,0.1070037,0.0006038584,0.0007928814,0.0002472913,0.0008251852,0.000006618134,0.0001289092,0.003036241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3831578,"threshold_uncertainty_score":0.9265926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02314064955390921,"score_gpt":0.3334324786407749,"score_spread":0.3102918290868656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}