{"id":"W2959633080","doi":"10.1007/s13181-019-00719-w","title":"Adverse Drug Events and Reactions Managed by Medical Toxicologists: an Analysis of the Toxicology Investigators Consortium (ToxIC) Registry, 2010–2016","year":2019,"lang":"en","type":"article","venue":"Journal of Medical Toxicology","topic":"Pharmacovigilance and Adverse Drug Reactions","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medicine; Emergency department; Emergency medicine; Retrospective cohort study; Intensive care unit; Drug reaction; Pediatrics; Internal medicine; Drug; Pharmacology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.005257981,0.0004140918,0.001340237,0.0006148826,0.0003000137,0.00001287804,0.00165723,0.00148575,0.009134145],"category_scores_gemma":[0.002957257,0.0003026222,0.0005745149,0.001094481,0.001879087,0.0003772422,0.0003959426,0.003559829,0.00004863883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002544138,"about_ca_system_score_gemma":0.001406128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000806828,"about_ca_topic_score_gemma":0.0002910445,"domain_scores_codex":[0.9929059,0.002500807,0.001857318,0.0005456953,0.001438453,0.0007518392],"domain_scores_gemma":[0.9935256,0.002178572,0.001816252,0.0005745597,0.0002689263,0.00163613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00183201,0.006646772,0.6017176,0.0003270682,0.01105096,0.0007717782,0.001312934,0.001973123,0.1590971,0.004630286,0.2040429,0.006597388],"study_design_scores_gemma":[0.01836036,0.001912241,0.2016875,0.0004217888,0.009271269,0.002540026,0.003737758,0.01517008,0.03147585,0.001469481,0.7125745,0.00137909],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.968785,0.0006583567,0.00007373268,0.02322193,0.005496496,0.0004650068,0.0001198511,0.00003946659,0.001140126],"genre_scores_gemma":[0.9857373,0.001998214,0.00005319775,0.009094697,0.0003920137,0.00002529551,0.00002459171,0.00003161706,0.002643102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5085316,"threshold_uncertainty_score":0.9999426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05365552942766577,"score_gpt":0.407930336274204,"score_spread":0.3542748068465382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}