{"id":"W2961103529","doi":"10.1097/pai.0000000000000794","title":"Simplified Molecular Subtyping of Medulloblastoma for Reduced Cost and Improved Turnaround Time","year":2019,"lang":"en","type":"article","venue":"Applied immunohistochemistry & molecular morphology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Subtyping; Immunohistochemistry; Medulloblastoma; Turnaround time; Immunostaining; Exon; Wnt signaling pathway; Biology; Mutation; Medicine; Internal medicine; Bioinformatics; Molecular biology; Oncology; Cancer research; Pathology; Genetics; Gene; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002646781,0.0009891032,0.001185429,0.004350492,0.0004021061,0.001147314,0.001142035,0.0004900708,0.004638179],"category_scores_gemma":[0.005445004,0.0006535723,0.001076552,0.001365434,0.0003468903,0.0010708,0.00142451,0.0006911766,0.002676765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007238684,"about_ca_system_score_gemma":0.001179858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006590446,"about_ca_topic_score_gemma":0.008656204,"domain_scores_codex":[0.9978598,0.0006494196,0.0002412966,0.0003657929,0.0007170724,0.0001667646],"domain_scores_gemma":[0.9968126,0.0007411211,0.0005187035,0.0006340632,0.0008766627,0.0004169363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002509374,0.0006235339,0.2166995,0.000839943,0.0002450154,0.003035667,0.0007979518,0.003978797,0.1816217,0.0005468648,0.008535779,0.5805659],"study_design_scores_gemma":[0.0008035452,0.004943837,0.6880227,0.0006128747,0.00141029,0.01864547,0.003484129,0.09432596,0.136764,0.002993987,0.04768069,0.0003125321],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7641718,0.006464603,0.2059404,0.002200921,0.0004479008,0.003593029,0.003495144,0.004298788,0.0093875],"genre_scores_gemma":[0.7131868,0.003664601,0.2716339,0.000474618,0.0003458954,0.001211811,0.006060974,0.0004082312,0.003013266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006590446,"threshold_uncertainty_score":0.01551622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005185000126348081,"score_gpt":0.2486425482427974,"score_spread":0.2434575481164493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}