{"id":"W2961111920","doi":"10.1002/art.41032","title":"Upadacitinib Versus Placebo or Adalimumab in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results of a Phase <scp>III</scp>, Double‐Blind, Randomized Controlled Trial","year":2019,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":436,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Adalimumab; Rheumatoid arthritis; Placebo; Internal medicine; Methotrexate; Rheumatology; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005155618,0.0007301738,0.005542525,0.001298707,0.000172703,0.0001186929,0.000336826,0.0004058874,0.0001613506],"category_scores_gemma":[0.007350261,0.0005574602,0.0003297454,0.0008028522,0.0008428962,0.0005521112,0.0001651055,0.0006474822,0.00007725167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008520751,"about_ca_system_score_gemma":0.0008315653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000981717,"about_ca_topic_score_gemma":0.002164631,"domain_scores_codex":[0.9907459,0.002879979,0.00277619,0.001214005,0.001070102,0.001313814],"domain_scores_gemma":[0.9879425,0.008795103,0.0008515705,0.0009839099,0.0005986905,0.0008282207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9653044,0.00182776,0.0008377241,0.0000505272,0.0007183212,0.0002229582,0.003664805,0.000007719062,0.00021131,0.0007455019,0.0001826033,0.02622641],"study_design_scores_gemma":[0.9688688,0.02443977,0.0002213938,0.002170519,0.00002263097,0.0002692461,0.001472758,0.0001844412,0.0007929642,0.0000957529,0.001138799,0.0003229365],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769166,0.004894623,0.00005130142,0.000452319,0.0005310614,0.01627674,0.0001264091,0.0001287968,0.0006222017],"genre_scores_gemma":[0.9721594,0.02454571,0.0009002193,0.00008285134,0.00001948364,0.001763184,0.0001942897,0.0001093967,0.0002254418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02590347,"threshold_uncertainty_score":0.9996877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890022007856599,"score_gpt":0.3133417629377253,"score_spread":0.2944415428591592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}