{"id":"W2961111920","doi":"10.1002/art.41032","title":"Upadacitinib Versus Placebo or Adalimumab in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results of a Phase <scp>III</scp>, Double‐Blind, Randomized Controlled Trial","year":2019,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":436,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Medicine; Adalimumab; Rheumatoid arthritis; Placebo; Internal medicine; Methotrexate; Rheumatology; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003139672,0.001557386,0.00439438,0.0004465995,0.0005011989,0.001465238,0.0009621264,0.002160704,0.005138646],"category_scores_gemma":[0.002716176,0.0006991016,0.002592005,0.0005454869,0.001031155,0.0009598374,0.000349693,0.002682404,0.0007216581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006038164,"about_ca_system_score_gemma":0.001071395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005944536,"about_ca_topic_score_gemma":0.001430477,"domain_scores_codex":[0.9987653,0.0007056211,0.0001301431,0.000177179,0.0001073241,0.0001144934],"domain_scores_gemma":[0.9984276,0.000600503,0.0004409942,0.0001010964,0.0001289395,0.0003008648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9853756,0.002232631,0.0002731159,0.001059837,0.001163737,0.00002595924,0.00002287509,0.0001106466,0.001059912,0.00003353217,0.0002958573,0.008346376],"study_design_scores_gemma":[0.9700646,0.02782951,0.0006700534,0.00004659385,0.0007343158,0.0000230622,0.000009125431,0.0001830279,0.0001706595,0.00003597981,0.0002252016,0.00000771543],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666175,0.02115345,0.001065193,0.001101896,0.001377474,0.005331956,0.0009829527,0.0001619134,0.002207781],"genre_scores_gemma":[0.9836232,0.007137982,0.001312222,0.001182499,0.0008609232,0.003418106,0.0007179548,0.00002077376,0.001726375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005138646,"threshold_uncertainty_score":0.01719046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01890022007856599,"score_gpt":0.3133417629377253,"score_spread":0.2944415428591592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}