{"id":"W2961116947","doi":"10.15252/embj.2018100871","title":"Redox signals at the ER–mitochondria interface control melanoma progression","year":2019,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Universität des Saarlandes; Deutsche Forschungsgemeinschaft","keywords":"Biology; Mitochondrion; Redox; Melanoma; Cell biology; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001444001,0.0002434749,0.0001581404,0.000209136,0.0001914892,0.0004892817,0.0001241183,0.0002319094,0.0008238688],"category_scores_gemma":[0.0001036089,0.00009094477,0.0001676683,0.0001250899,0.0001689212,0.00032307,0.0002682948,0.0003798576,0.0003086478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002807332,"about_ca_system_score_gemma":0.0001629229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005214511,"about_ca_topic_score_gemma":0.0006761389,"domain_scores_codex":[0.9999118,0.00001428066,0.000005578458,0.00002637867,0.0000170199,0.0000249057],"domain_scores_gemma":[0.9999375,0.000004238047,0.00002720304,0.000003165969,0.0000131127,0.00001482333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001915244,0.00002395561,0.003749782,0.00005046181,0.00000959335,0.00009937103,0.0000626715,0.0001727171,0.990064,0.0004094998,0.000146581,0.005019912],"study_design_scores_gemma":[0.00004857533,0.0003414051,0.1640192,0.00005228761,0.0000753007,0.0007068738,0.0006326268,0.007934025,0.8064024,0.001893929,0.01786141,0.00003212796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865802,0.006758566,0.003912433,0.0002427985,0.00004213882,0.00002602505,0.0003320686,0.0001218201,0.001983953],"genre_scores_gemma":[0.99578,0.001604043,0.0009009063,0.00004306583,0.00000862896,0.000009783219,0.0001443756,0.00001067608,0.001498401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008238688,"threshold_uncertainty_score":0.002756059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006239839379701728,"score_gpt":0.2747488480149298,"score_spread":0.268509008635228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}