{"id":"W2961345630","doi":"10.1038/s41598-019-45627-9","title":"Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research; Deutsche Krebshilfe; Bundesministerium für Bildung und Forschung; Bundesministerium für Bildung, Wissenschaft und Kultur; Deutsche Forschungsgemeinschaft; Government of Canada; Wellcome Trust; Deutschen Konsortium für Translationale Krebsforschung; Wellcome","keywords":"Cell biology; Signal transducing adaptor protein; T-cell receptor; Kinase; PLK1; Cell cycle; Biology; T cell; Cell division; Cell; Phosphorylation; Chemistry; Immune system; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009999151,0.0004073765,0.0001511215,0.0001806693,0.0003423985,0.0004305702,0.0001844701,0.0002282145,0.002280973],"category_scores_gemma":[0.00010312,0.0001554215,0.000171253,0.0001227952,0.0002164706,0.0004013184,0.0003804403,0.0005041913,0.000916753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003905225,"about_ca_system_score_gemma":0.0002739383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002185177,"about_ca_topic_score_gemma":0.0003665233,"domain_scores_codex":[0.9999182,0.000009469384,0.000006688104,0.00002583783,0.00001584968,0.00002396779],"domain_scores_gemma":[0.9999059,0.000009759082,0.00003403328,0.000006693618,0.000009106272,0.00003444125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009825505,0.000007767868,0.0003001336,0.00003512368,0.000002371616,0.00008493783,0.00001142536,0.00007592584,0.9979285,0.0002490479,0.00005550612,0.001150963],"study_design_scores_gemma":[0.00001583375,0.00006216695,0.006924625,0.00000739296,0.000007873427,0.0004122684,0.00003300481,0.001412933,0.9879134,0.0001748609,0.003031126,0.000004502921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903853,0.002009014,0.005068008,0.0001589543,0.00003013041,0.00001555626,0.0002539105,0.0001099824,0.001969129],"genre_scores_gemma":[0.9957421,0.0006445388,0.001310807,0.00002135882,0.000008480312,0.00001376509,0.0003155264,0.00001673786,0.00192668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002280973,"threshold_uncertainty_score":0.007630646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007750908731301093,"score_gpt":0.2298072677390137,"score_spread":0.2220563590077126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}