{"id":"W2961576630","doi":"10.1007/s10528-019-09932-2","title":"Biological Effects of Single-Nucleotide Polymorphisms in the Drosophila melanogaster Malic Enzyme Locus","year":2019,"lang":"en","type":"article","venue":"Biochemical Genetics","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Drosophila melanogaster; Genetics; Locus (genetics); Single-nucleotide polymorphism; Malic enzyme; Human genetics; Nucleotide; Melanogaster; Enzyme; Genotype; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000142975,0.000161242,0.0002385836,0.00005448108,0.00003289718,0.00001042773,0.0006702203,0.000222923,0.0000549277],"category_scores_gemma":[0.0002872885,0.0001026898,0.00008537652,0.0002840604,0.000577208,0.00002066742,0.0002101395,0.0003303011,0.0001709298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001187374,"about_ca_system_score_gemma":0.00001955549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002054347,"about_ca_topic_score_gemma":1.885059e-7,"domain_scores_codex":[0.9982964,0.00044523,0.0002470045,0.0004441766,0.0001635005,0.0004036709],"domain_scores_gemma":[0.9984485,0.000974774,0.00006618769,0.0004386017,0.00001813681,0.00005380068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008109526,0.0002208443,0.004077604,0.00001936249,0.000002690195,0.00002012881,0.00005170779,0.000002046618,0.99499,0.0002223715,0.0002084764,0.0001036686],"study_design_scores_gemma":[0.0003995823,0.0007022704,0.008381327,0.00001655241,0.000003689564,0.000028256,0.000005174204,0.00001824251,0.9893056,0.000648084,0.0003798369,0.0001113619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981123,0.0004141407,0.000002898294,0.0002827287,0.0002278982,0.0003836285,0.000007234837,0.0000167541,0.0005524508],"genre_scores_gemma":[0.9981277,0.0001113468,0.00002349273,0.001553432,0.00008624193,0.0000146898,0.000003881387,0.00001178755,0.00006741954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005684381,"threshold_uncertainty_score":0.4187567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03165366674680766,"score_gpt":0.2618183072876621,"score_spread":0.2301646405408544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}