{"id":"W2961690031","doi":"10.1182/blood.v128.22.1687.1687","title":"Down Syndrome AML Is Unique in Phenotype Both at Diagnosis and in Post Chemotherapy Regeneration","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Hospital for Sick Children","funders":"","keywords":"Medicine; Internal medicine; Down syndrome; Chemotherapy; Oncology; Myeloid leukemia; Immunophenotyping; Minimal residual disease; Bone marrow; Leukemia; Immunology; Gastroenterology; Pathology; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013454,0.0001703004,0.0001626314,0.0004582579,0.0002069487,0.0003060928,0.0001206853,0.0001880583,0.001849364],"category_scores_gemma":[0.0006372866,0.00007238724,0.0001103289,0.0002896158,0.0001871312,0.0001127128,0.0002684974,0.0001487141,0.0002269525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001410049,"about_ca_system_score_gemma":0.0001280855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004593136,"about_ca_topic_score_gemma":0.0006072234,"domain_scores_codex":[0.9998581,0.00001576426,0.00001985422,0.00004490804,0.00003269433,0.00002865013],"domain_scores_gemma":[0.9997202,0.00008803645,0.00007704923,0.0000192587,0.0000304562,0.00006486679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007640842,0.00006765071,0.8725215,0.00003840355,0.00003363548,0.01771154,0.0002488805,0.0001506107,0.08934335,0.0003093353,0.0003394804,0.01847156],"study_design_scores_gemma":[0.00002566708,0.0004422716,0.8990685,0.00001249805,0.00005995795,0.08554064,0.000206975,0.0003246704,0.01103921,0.0002172091,0.003052991,0.000009443353],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998881,0.0000877983,0.0002206363,0.00001395603,0.000002935647,0.000008813751,0.0001544664,0.00000639156,0.0006240172],"genre_scores_gemma":[0.999213,0.0000461913,0.0002510263,0.00001604249,0.000004344043,0.000006164052,0.0002464449,0.000002851152,0.0002140856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001849364,"threshold_uncertainty_score":0.006186724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307528145618604,"score_gpt":0.2655184290061154,"score_spread":0.2524431475499294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}