{"id":"W2961930566","doi":"10.3390/cancers11070960","title":"Furanoic Lipid F-6, A Novel Anti-Cancer Compound that Kills Cancer Cells by Suppressing Proliferation and Inducing Apoptosis","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; Hospital for Sick Children","funders":"Kuwait University; Hospital for Sick Children; Kuwait Foundation for the Advancement of Sciences; Cystic Fibrosis Canada","keywords":"Apoptosis; PI3K/AKT/mTOR pathway; Cancer cell; Protein kinase B; Cancer; Cancer research; Molecular biology; Cell growth; Cell culture; p38 mitogen-activated protein kinases; MAPK/ERK pathway; Western blot; Chemistry; Programmed cell death; Biology; Biochemistry; Medicine; Signal transduction; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007623598,0.0003010578,0.000163455,0.0002860285,0.0001310022,0.0001693764,0.0001189227,0.0003426457,0.0005987176],"category_scores_gemma":[0.00004216096,0.00007619601,0.0001867665,0.0001470186,0.0001300507,0.0001746954,0.0001230809,0.0003597704,0.0002182968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002231879,"about_ca_system_score_gemma":0.0001327016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003549431,"about_ca_topic_score_gemma":0.0006361461,"domain_scores_codex":[0.9999615,0.0000048004,0.000002669874,0.000009441129,0.00001228034,0.000009403586],"domain_scores_gemma":[0.9999746,0.000002790419,0.000009225035,0.000001733655,0.000004804338,0.000006906228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001366521,0.00004232884,0.0003191091,0.0001180807,0.000008017682,0.0001197104,0.00001230079,0.0002022393,0.9838834,0.0002360371,0.0001531539,0.01476905],"study_design_scores_gemma":[0.00003094732,0.0009659227,0.002974841,0.00002012548,0.00002528587,0.0009337447,0.00002400113,0.0005138567,0.9718438,0.0001372763,0.02251958,0.00001057423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9122675,0.06451523,0.01531534,0.000635488,0.0001403929,0.0001268718,0.0008126152,0.000200013,0.005986485],"genre_scores_gemma":[0.9607261,0.02371326,0.008663099,0.0002328371,0.0000545491,0.00005553911,0.0006197257,0.00001378453,0.005921171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005987176,"threshold_uncertainty_score":0.002002954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01177158118573969,"score_gpt":0.2432285241921318,"score_spread":0.2314569430063921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}