{"id":"W2962116267","doi":"10.1371/journal.pone.0219835","title":"Hepatocellular heme oxygenase 1 deficiency does not affect inflammatory hepcidin regulation in mice","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Hepcidin; Inflammation; Heme oxygenase; Heme; Hepatocyte; Regulator; Knockout mouse; Chemistry; Endocrinology; Immunology; Internal medicine; Biology; Medicine; Biochemistry; Receptor; Enzyme; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005277412,0.001133298,0.000776344,0.001934692,0.0005952598,0.001079998,0.00100525,0.001893526,0.006478864],"category_scores_gemma":[0.0004093953,0.0007826419,0.0007795822,0.0004700405,0.001426492,0.0008654111,0.0005911312,0.002820844,0.001610871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001053416,"about_ca_system_score_gemma":0.0005763796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001131535,"about_ca_topic_score_gemma":0.002095221,"domain_scores_codex":[0.9991466,0.00009982358,0.00008851018,0.000297557,0.0001723998,0.000195189],"domain_scores_gemma":[0.9986696,0.0001566053,0.0005026333,0.0001514649,0.00007092163,0.0004487518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001108523,0.0003275943,0.0003857589,0.00009876997,0.00002771717,0.0002720344,0.00007478699,0.0001667875,0.9946826,0.0006748927,0.0002503454,0.001930097],"study_design_scores_gemma":[0.0005642455,0.001566393,0.008530056,0.00007196225,0.0001299433,0.001363059,0.0001851896,0.002418546,0.9757317,0.0005769735,0.008812351,0.0000496742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763998,0.001982233,0.009200711,0.001025628,0.0002580768,0.0002486962,0.00634269,0.00108753,0.003454591],"genre_scores_gemma":[0.9630789,0.001834341,0.007785895,0.000629045,0.00008943844,0.0005532234,0.004558908,0.0006338499,0.02083639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006478864,"threshold_uncertainty_score":0.02167398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410832134319243,"score_gpt":0.2036571029841792,"score_spread":0.1895487816409868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}