{"id":"W2962144253","doi":"10.1021/acs.inorgchem.9b00770","title":"Metal–Organocatalyst for Detoxification of Phosphorothioate Pesticides: Demonstration of Acetylcholine Esterase Activity","year":2019,"lang":"en","type":"article","venue":"Inorganic Chemistry","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut interdisciplinaire d'innovation technologique; Université de Sherbrooke","funders":"Department of Biotechnology, Ministry of Science and Technology, India","keywords":"Chemistry; Detoxification (alternative medicine); Esterase; Pesticide; Acetylcholine; Catalysis; Organic chemistry; Combinatorial chemistry; Enzyme; Pharmacology; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001994826,0.0004011453,0.0002430101,0.000178892,0.00009388779,0.0002332744,0.000336895,0.0004604799,0.0007593073],"category_scores_gemma":[0.0002644415,0.0001547932,0.0001856126,0.000223711,0.0002341608,0.0001873412,0.0002139616,0.0004233317,0.0001908053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002628757,"about_ca_system_score_gemma":0.0001694957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009335,"about_ca_topic_score_gemma":0.001427679,"domain_scores_codex":[0.9997934,0.00002769809,0.00001886307,0.0000551166,0.00007206888,0.00003286398],"domain_scores_gemma":[0.9998829,0.00002004092,0.00004037604,0.00001129305,0.00002796643,0.0000172669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001703248,0.000007765008,0.00002539678,0.00004016267,0.00000267927,0.00002342349,0.00001089968,0.00002337404,0.999338,0.00002737561,0.00001264757,0.0004713342],"study_design_scores_gemma":[0.0000025103,0.00009722143,0.000184994,0.00000234394,0.000003618033,0.00004232228,0.000005920407,0.0001947907,0.9991166,0.000004827517,0.0003435503,0.000001395637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98469,0.00240917,0.01027971,0.000104699,0.0000361459,0.00004947989,0.0001677109,0.000208734,0.002054414],"genre_scores_gemma":[0.9887344,0.001108225,0.007709643,0.00003457361,0.000008584265,0.00003350175,0.0001467224,0.00002309726,0.002201129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001009335,"threshold_uncertainty_score":0.002540112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01285023441648533,"score_gpt":0.2221428712415189,"score_spread":0.2092926368250336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}