{"id":"W2962144821","doi":"10.1139/cjpp-2019-0006","title":"The contribution of phosphodiesterases to cardiac dysfunction in rats with metabolic syndrome induced by a high-carbohydrate diet","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Internal medicine; Endocrinology; Phosphodiesterase; Basal (medicine); Phosphodiesterase 3; Homeostasis; Insulin resistance; Biology; Metabolic syndrome; Intracellular; Glucose homeostasis; Catabolism; Diabetes mellitus; Medicine; Metabolism; Enzyme; Cell biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002166857,0.0001059996,0.0002628552,0.00008774936,0.00007966863,0.000006856978,0.00008203788,0.0001114711,0.00003904398],"category_scores_gemma":[0.00001818258,0.00007349885,0.0000410215,0.0001176858,0.000105475,0.00001082124,0.0000135782,0.0001276697,0.000001961859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002165801,"about_ca_system_score_gemma":0.0002459228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004514958,"about_ca_topic_score_gemma":0.001216332,"domain_scores_codex":[0.9992005,0.0001802885,0.0002332811,0.0001381906,0.00004336033,0.0002043295],"domain_scores_gemma":[0.9993953,0.00004298224,0.0001750373,0.00008326043,0.0001504078,0.0001530286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001045949,0.00001308399,0.005614921,0.000006826941,0.0001465628,0.00000353609,0.00004805187,0.0002266776,0.9917749,0.00007045743,0.0008507807,0.0001983197],"study_design_scores_gemma":[0.001437325,0.00223715,0.09990143,0.00001762239,0.00006592381,0.00002744878,0.00006299504,0.00001428594,0.8808388,0.00008401811,0.01518489,0.0001280694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962593,0.001964656,0.00001502578,0.0004171216,0.001112003,0.00019958,0.00002009736,0.000001015369,0.00001115281],"genre_scores_gemma":[0.9991559,0.0002609341,0.000007734401,0.0003996408,0.00007092289,0.00001045086,0.00003213393,0.000007142122,0.00005517124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.110936,"threshold_uncertainty_score":0.2997196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004299290269706003,"score_gpt":0.2170233483017991,"score_spread":0.2127240580320931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}