{"id":"W2963015093","doi":"10.1016/s1470-2045(19)30395-x","title":"Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":456,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Hôpital Notre-Dame; Université de Sherbrooke","funders":"National Health and Medical Research Council; Canadian Cancer Society Research Institute; KWF Kankerbestrijding; Strong; European SocieTy for Radiotherapy and Oncology; Agenzia Italiana del Farmaco, Ministero della Salute; National Cancer Research Institute; Cancer Australia; Cancer Research UK; Merck","keywords":"Medicine; Endometrial cancer; Radiation therapy; Chemoradiotherapy; Clinical endpoint; Carboplatin; Oncology; Internal medicine; Lymphadenectomy; Post-hoc analysis; Gynecology; Surgery; Clinical trial; Cancer; Chemotherapy; Cisplatin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01255027,0.00128304,0.002283945,0.0003903576,0.0003004418,0.001003424,0.0008047202,0.001138794,0.003737418],"category_scores_gemma":[0.0136211,0.000412214,0.006422355,0.000578713,0.0009009478,0.001052014,0.0007477497,0.002156209,0.0003666866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008055039,"about_ca_system_score_gemma":0.001249042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005324525,"about_ca_topic_score_gemma":0.00136342,"domain_scores_codex":[0.991355,0.007255737,0.0004189256,0.0004405977,0.0002340148,0.000295688],"domain_scores_gemma":[0.9920912,0.004191398,0.001952191,0.0009440975,0.0002590144,0.0005621366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9777635,0.001176801,0.002988759,0.0006334278,0.006955301,0.00003831749,0.00005730224,0.0006274563,0.0006265143,0.00009697167,0.0003909256,0.008644678],"study_design_scores_gemma":[0.870609,0.09826156,0.01491523,0.0001849349,0.01064065,0.0001189224,0.0000778286,0.002135123,0.0006616213,0.0009978253,0.00134251,0.00005474099],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850175,0.006142969,0.001642236,0.0005463199,0.0003559261,0.003852799,0.001228333,0.00006053879,0.001153425],"genre_scores_gemma":[0.9875163,0.001338732,0.002402307,0.000519846,0.0002365937,0.005619185,0.001073193,0.00002327816,0.001270536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01255027,"threshold_uncertainty_score":0.06637293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03306297968360868,"score_gpt":0.3534208534692313,"score_spread":0.3203578737856226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}