{"id":"W2963553330","doi":"10.1371/journal.pone.0220045","title":"Structure and functional analysis of a bacterial adhesin sugar-binding domain","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Queen's University; Imperial College London; Canadian Light Source","keywords":"Isothermal titration calorimetry; Bacterial adhesin; Chemistry; Biochemistry; Ligand (biochemistry); Binding domain; Binding site; Stereochemistry; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002622663,0.00007429117,0.000162072,0.00004735835,0.00001813624,0.00001007305,0.00003916053,0.000109163,0.0003728728],"category_scores_gemma":[0.00001541385,0.00006412974,0.00004518667,0.000125153,0.00002807782,0.000003294752,0.00004081523,0.00003961853,0.000001474697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004580351,"about_ca_system_score_gemma":0.000009925751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002313301,"about_ca_topic_score_gemma":0.000003607694,"domain_scores_codex":[0.9994963,0.00001655902,0.0001176225,0.0001824673,0.0001030885,0.00008400017],"domain_scores_gemma":[0.9997398,0.000005332122,0.00006321263,0.0001133907,0.00004448004,0.00003377301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001217339,0.00003007474,0.03204978,0.00002837722,0.0005642411,8.501515e-8,0.00001624706,9.423966e-7,0.967091,0.00003402579,0.000008094949,0.00005543088],"study_design_scores_gemma":[0.0002409821,0.00006961339,0.1026588,0.000008451926,0.0002156251,6.438223e-7,0.000009057183,0.00004142434,0.896594,0.00003964496,0.00004094188,0.00008081023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996089,0.0000359783,0.0000191519,0.00003799545,0.00003216246,0.0000727796,0.0001423062,0.000003704141,0.00004701897],"genre_scores_gemma":[0.9975126,0.0000129674,0.0005367444,0.00003126421,0.0001123963,0.000001424011,0.001619184,0.000005599153,0.0001678613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.070609,"threshold_uncertainty_score":0.4082696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.011099676369245,"score_gpt":0.1870826384655322,"score_spread":0.1759829620962872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}