{"id":"W2963638759","doi":"10.1002/mc.23087","title":"Antitumour effects of metformin and curcumin in human papillomavirus positive and negative head and neck cancer cells","year":2019,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Curcumin; Metformin; Biology; Head and neck squamous-cell carcinoma; Cancer; Cancer research; Apoptosis; Carcinogenesis; Cell; Cell growth; Cell culture; Drug; Head and neck cancer; Internal medicine; Pharmacology; Oncology; Medicine; Endocrinology; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001739273,0.0002511198,0.0003915979,0.0003363262,0.0001699891,0.0001601417,0.0001559926,0.0002239115,0.0009331738],"category_scores_gemma":[0.0001428749,0.000114311,0.000331884,0.0002709324,0.0001094758,0.0001625846,0.0001824426,0.0003248416,0.0002032775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002059367,"about_ca_system_score_gemma":0.0002961468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001852402,"about_ca_topic_score_gemma":0.003756194,"domain_scores_codex":[0.9998538,0.00003529977,0.00002129453,0.00002662783,0.0000376311,0.00002518],"domain_scores_gemma":[0.9999088,0.00002376029,0.0000132434,0.00001202366,0.0000252577,0.00001690915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001001164,0.0003126986,0.0008207159,0.0003224767,0.00003874944,0.0001314703,0.00006940046,0.0002425224,0.9879829,0.0000734703,0.0002654337,0.008739054],"study_design_scores_gemma":[0.0001130794,0.0037552,0.01818361,0.00002184035,0.00008485465,0.0002264047,0.000106457,0.0007370278,0.9718759,0.00002774176,0.004855696,0.00001225704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936097,0.003840617,0.0003995073,0.00009340214,0.00007300777,0.00004404694,0.0003896922,0.00002406051,0.001526132],"genre_scores_gemma":[0.9938347,0.002411046,0.000971488,0.00005695171,0.00001585878,0.00005513226,0.0005433778,0.000005402424,0.002106117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001852402,"threshold_uncertainty_score":0.003683209,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004206163430925765,"score_gpt":0.2363453971661101,"score_spread":0.2321392337351843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}