{"id":"W2963748700","doi":"10.1378/chest.136.4_meetingabstracts.93s-b","title":"EFFICACY AND SAFETY OF THE PHOSPHODIESTERASE 4 INHIBITOR ROFLUMILAST IN PATIENTS WITH SYMPTOMATIC CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN THE M2-125 STUDY","year":2009,"lang":"en","type":"article","venue":"CHEST Journal","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Roflumilast; Medicine; Pulmonary disease; Phosphodiesterase inhibitor; Intensive care medicine; Phosphodiesterase; Disease; Internal medicine; cGMP-specific phosphodiesterase type 5; Sildenafil","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001398179,0.000931316,0.002431201,0.0003057148,0.0003085459,0.001106548,0.0006215089,0.001242029,0.001236456],"category_scores_gemma":[0.001366958,0.0004315822,0.002141654,0.0003329704,0.000600701,0.0008863655,0.0003162484,0.001794096,0.0003174661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006300372,"about_ca_system_score_gemma":0.0006559613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007979201,"about_ca_topic_score_gemma":0.00159891,"domain_scores_codex":[0.9992821,0.0003592894,0.00005831395,0.0001055792,0.00007821478,0.0001165094],"domain_scores_gemma":[0.9992449,0.0002049504,0.0001637033,0.00007977165,0.00005124614,0.000255429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8968604,0.004530578,0.02970976,0.0008608195,0.004593898,0.000372045,0.0001395234,0.0008406309,0.01387624,0.0002671628,0.001549554,0.04639938],"study_design_scores_gemma":[0.5456907,0.1926699,0.2445034,0.0001680999,0.007266891,0.0005173227,0.0001801929,0.001728514,0.002986165,0.0004566469,0.00370809,0.0001241282],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924963,0.005003233,0.0001467798,0.000323739,0.00008779152,0.0001172249,0.0005073512,0.00002356425,0.001294034],"genre_scores_gemma":[0.9966882,0.00130023,0.0001248255,0.000380887,0.0001851215,0.00009232215,0.0008011142,0.000007560563,0.0004197652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002431201,"threshold_uncertainty_score":0.007394373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005072882799196472,"score_gpt":0.2229811761379868,"score_spread":0.2179082933387904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}