{"id":"W2963901310","doi":"10.3389/fcell.2019.00154","title":"What Is Nuclear Factor Kappa B (NF-κB) Doing in and to the Mitochondrion?","year":2019,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":342,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research; Alzheimer Society of Manitoba; Alzheimer Society; Alzheimer's Society; Research Manitoba","keywords":"Mitochondrion; Biology; Function (biology); Cell biology; NFKB1; NF-κB; Programmed cell death; mitochondrial fusion; Gene; Genetics; Mitochondrial DNA; Signal transduction; Apoptosis; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006698862,0.0007790271,0.001299962,0.001508382,0.0004443285,0.001866938,0.0008844457,0.00165144,0.002265378],"category_scores_gemma":[0.000866532,0.0002424681,0.0003559072,0.001687255,0.001551415,0.003731985,0.000653335,0.002316574,0.002307494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008761433,"about_ca_system_score_gemma":0.001519831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001346009,"about_ca_topic_score_gemma":0.001565008,"domain_scores_codex":[0.9998055,0.00003837273,0.00002909699,0.00005296746,0.00005001542,0.00002400457],"domain_scores_gemma":[0.9996159,0.0001956253,0.00004431227,0.00001656536,0.00008511594,0.00004249051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009664494,0.0000339191,0.0002095455,0.01764452,0.00004981089,0.0002344175,0.0002070701,0.000224231,0.002748197,0.01285077,0.0373012,0.9283997],"study_design_scores_gemma":[0.000006644043,0.00006224705,0.0004905834,0.003270651,0.00003925098,0.00120838,0.0001779172,0.00004081596,0.0003653261,0.006988467,0.9873297,0.00001993725],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005233518,0.9975767,0.0001194133,0.0009600601,0.0004660071,0.000001501047,0.000011461,0.000004836971,0.0008076598],"genre_scores_gemma":[0.000427651,0.9983135,0.0001008707,0.0004011439,0.0003815782,0.000002275786,0.00001353754,0.000001209818,0.0003582451],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002265378,"threshold_uncertainty_score":0.007578373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01809205691763559,"score_gpt":0.2631157975842076,"score_spread":0.245023740666572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}