{"id":"W2963917964","doi":"10.1093/infdis/jiz241","title":"Immunogenicity, Lot Consistency, and Extended Safety of rVSVΔG-ZEBOV-GP Vaccine: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults","year":2019,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Merck Sharp and Dohme; U.S. Department of Health and Human Services","keywords":"Immunogenicity; Medicine; Ebola vaccine; Virology; Vaccination; Titer; Placebo; Antibody; Neutralizing antibody; Immunology; Ebola virus; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002795199,0.0002588225,0.001816217,0.0006228095,0.000153615,0.00003501892,0.0001505535,0.0000781122,0.0002542435],"category_scores_gemma":[0.0006246202,0.0001477271,0.0004829368,0.0004766973,0.0001614454,0.0001849788,0.0000996142,0.000555681,0.00001071988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510355,"about_ca_system_score_gemma":0.0005351674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001077755,"about_ca_topic_score_gemma":0.0003651914,"domain_scores_codex":[0.9964365,0.0009932962,0.00148342,0.0001914836,0.0005643536,0.0003309783],"domain_scores_gemma":[0.9965236,0.001410023,0.0007819842,0.0003549563,0.0006679827,0.0002614472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9473147,0.005674204,0.04275687,0.0001666698,0.001183066,0.00004754836,0.0006084397,0.00009068099,0.0004555916,0.00003889298,0.00004138105,0.001621978],"study_design_scores_gemma":[0.9674752,0.01248837,0.01527431,0.0003200145,0.001309014,0.0007069464,0.001552799,0.0004959797,0.0001128917,0.0001128295,0.00001353683,0.0001380541],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889675,0.004379496,0.00005315434,0.000383921,0.0002238697,0.005241334,0.00001469373,0.00001983825,0.0007161636],"genre_scores_gemma":[0.9972413,0.00233432,0.000005434268,0.0001284391,0.0001192124,0.00006073224,0.000003320403,0.00002542473,0.00008181584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02748256,"threshold_uncertainty_score":0.6024136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01637573060381659,"score_gpt":0.3420336245293484,"score_spread":0.3256578939255318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}