{"id":"W2963917964","doi":"10.1093/infdis/jiz241","title":"Immunogenicity, Lot Consistency, and Extended Safety of rVSVΔG-ZEBOV-GP Vaccine: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study in Healthy Adults","year":2019,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Merck Sharp and Dohme; U.S. Department of Health and Human Services","keywords":"Immunogenicity; Medicine; Ebola vaccine; Virology; Vaccination; Titer; Placebo; Antibody; Neutralizing antibody; Immunology; Ebola virus; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003471537,0.001341207,0.002542578,0.0004610048,0.0006065684,0.0006736908,0.000837289,0.001754621,0.003719192],"category_scores_gemma":[0.002069875,0.0008788217,0.001563276,0.0003655679,0.001202099,0.0009635551,0.0004300052,0.001668894,0.0006338204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000421305,"about_ca_system_score_gemma":0.000961005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004084703,"about_ca_topic_score_gemma":0.0006393492,"domain_scores_codex":[0.9988086,0.0005609608,0.0001247656,0.0002386849,0.000136059,0.0001308631],"domain_scores_gemma":[0.9980348,0.0004971799,0.0006244382,0.0002005701,0.0002124023,0.0004307693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9555438,0.02154056,0.00148172,0.0004220445,0.0005383687,0.00002402975,0.00006891743,0.0001959781,0.009960161,0.00002567101,0.0002021409,0.009996701],"study_design_scores_gemma":[0.615849,0.3760242,0.005576772,0.00002389173,0.000360651,0.00003045325,0.00002303094,0.0002383236,0.001475594,0.0000640792,0.0003176581,0.00001637176],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936232,0.001186242,0.0005942872,0.00009610816,0.0001387322,0.003652584,0.0003666593,0.00005458517,0.0002875524],"genre_scores_gemma":[0.9901716,0.0008186018,0.001889244,0.0004401591,0.000248555,0.005188543,0.0004441341,0.00002065288,0.0007784306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003719192,"threshold_uncertainty_score":0.01835948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01637573060381659,"score_gpt":0.3420336245293484,"score_spread":0.3256578939255318,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}