{"id":"W2964093992","doi":"10.1523/eneuro.0035-19.2019","title":"GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Walloon excellence in life sciences and biotechnology; National Institute on Drug Abuse; Conseil Régional d'Alsace; Fonds Unique Interministériel; Canada Research Chairs; Canada Foundation for Innovation; Fondation pour la Recherche Médicale; Fonds De La Recherche Scientifique - FNRS","keywords":"Medium spiny neuron; Striatum; Nucleus accumbens; Open field; Neuroscience; Motor coordination; Pharmacology; Psychology; Biology; Endocrinology; Dopamine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006373154,0.0001490341,0.0001542935,0.00004572536,0.00003503181,0.00003064945,0.00008259595,0.0001161552,0.00007021124],"category_scores_gemma":[0.00006216158,0.0001377408,0.00002633591,0.00006982272,0.00003571287,0.000005373615,0.0001223426,0.0001027702,0.000005846162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004630865,"about_ca_system_score_gemma":0.00002765531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000201564,"about_ca_topic_score_gemma":0.00001999343,"domain_scores_codex":[0.9991587,0.00006303684,0.0001217663,0.0003822728,0.00008444636,0.0001897156],"domain_scores_gemma":[0.999632,0.00001963682,0.00004123835,0.0001900044,0.00004287269,0.00007422756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007586904,0.00003209919,0.01279361,0.00001207486,0.000008058411,0.000007439487,0.00004167591,0.000004847047,0.9857473,0.00002811653,0.00004908766,0.00119977],"study_design_scores_gemma":[0.0006594121,0.001181967,0.2746047,0.00001870463,0.00002428168,0.00002342962,0.00003572449,0.00009289575,0.7215028,0.00007208522,0.001553524,0.0002304367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985327,0.0004607439,0.00001749161,0.00004651787,0.0005473833,0.000264692,0.000004925399,0.00001040813,0.0001151807],"genre_scores_gemma":[0.9987306,0.0003050519,0.000121184,0.0001123046,0.00009653393,0.000008302811,0.00002232648,0.00002630937,0.0005773748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2642445,"threshold_uncertainty_score":0.5616907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006368443027636973,"score_gpt":0.2249313284240109,"score_spread":0.2185628853963739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}