{"id":"W2964170275","doi":"10.1101/714170","title":"NK cells prevent the formation of teratomas derived from human induced pluripotent stem cells","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé","keywords":"Induced pluripotent stem cell; Haematopoiesis; Peripheral blood mononuclear cell; Stem cell; Biology; Adoptive cell transfer; Immune system; Immunology; Amniotic epithelial cells; Cancer research; Transplantation; Hematopoietic stem cell transplantation; Adult stem cell; Embryonic stem cell; Cell biology; Medicine; T cell; Internal medicine; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001850847,0.0001792085,0.0001530992,0.0001602045,0.00006904238,0.000196568,0.0001213481,0.0001621869,0.001407785],"category_scores_gemma":[0.0001327402,0.00007839571,0.0001597889,0.00008259965,0.0001566482,0.00008837949,0.0001626368,0.0004757695,0.0004571982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007014188,"about_ca_system_score_gemma":0.0001303367,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002655727,"about_ca_topic_score_gemma":0.0002722195,"domain_scores_codex":[0.9998682,0.00002880941,0.000020685,0.00002313857,0.00004317094,0.00001596949],"domain_scores_gemma":[0.9998505,0.00004586116,0.00003600213,0.00003021097,0.00001566166,0.00002174774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000548445,0.00001579904,0.0001874474,0.00003351848,0.000004978862,0.00004297337,0.00001127742,0.00006182255,0.9978222,0.0001276051,0.00004946129,0.001588198],"study_design_scores_gemma":[0.000008364448,0.00009348393,0.001172626,0.000004513861,0.000009182705,0.0001338716,0.000006684536,0.0003772924,0.9968042,0.0000320381,0.001356957,7.866193e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769686,0.00215606,0.01586135,0.0001177379,0.00006862343,0.0001036389,0.001081454,0.000245445,0.003397179],"genre_scores_gemma":[0.9886905,0.0007686652,0.005221092,0.00005628506,0.00001201256,0.00003682119,0.0008996742,0.00004701981,0.004267848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001407785,"threshold_uncertainty_score":0.004709482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01830332715388636,"score_gpt":0.2343719177914515,"score_spread":0.2160685906375652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}