{"id":"W2964322263","doi":"10.1016/j.vetmic.2019.07.014","title":"Immunoproteomic analysis of Lawsonia intracellularis identifies candidate neutralizing antibody targets for use in subunit vaccine development","year":2019,"lang":"en","type":"article","venue":"Veterinary Microbiology","topic":"Veterinary medicine and infectious diseases","field":"Veterinary","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lawsonia intracellularis; Biology; Recombinant DNA; Bacterial outer membrane; Microbiology; Protein subunit; Escherichia coli; Molecular biology; Virology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001291056,0.0003783584,0.0002409994,0.0002467899,0.0001555815,0.0002973347,0.0001675268,0.0002568364,0.0004877683],"category_scores_gemma":[0.0001824223,0.00007289033,0.0002605335,0.0002014151,0.0001365104,0.0001904395,0.0001448091,0.0003702338,0.000193613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923582,"about_ca_system_score_gemma":0.0002621446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001611006,"about_ca_topic_score_gemma":0.001990892,"domain_scores_codex":[0.9999286,0.00000689429,0.000004802879,0.00001020298,0.00002934845,0.00002015749],"domain_scores_gemma":[0.9999187,0.00001322011,0.00002406097,0.000006546231,0.00002693771,0.0000104602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006598294,0.00003686469,0.00127701,0.0000237076,0.000005713465,0.0000452114,0.00001518065,0.0001080127,0.9968317,0.00002508144,0.00004582013,0.001519765],"study_design_scores_gemma":[0.00001863834,0.0008881912,0.05304592,0.00002041702,0.00007102061,0.0004752084,0.0002395403,0.003527194,0.938723,0.0001414936,0.002840713,0.000008593333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963211,0.0004227111,0.001742963,0.0001007727,0.00002338415,0.00004418155,0.0006051628,0.00002639104,0.0007133022],"genre_scores_gemma":[0.9941215,0.0003384301,0.002501636,0.0001072762,0.00000774064,0.00002532642,0.001740724,0.000009891804,0.001147475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001611006,"threshold_uncertainty_score":0.003203213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03869850870603246,"score_gpt":0.3222677149681805,"score_spread":0.283569206262148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}