{"id":"W2964380626","doi":"10.1016/j.euroneuro.2018.08.190","title":"F110DNA METHYLATION OF STRESS SYSTEM GENES (CRHR1, CRHR2, FKBP5, NR3C1, NR3C2, SKA2) MAY BE ASSOCIATED WITH ANTIDEPRESSANT TREATMENT OUTCOME IN CLINICAL DEPRESSION","year":2019,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Endocrinology; Internal medicine; Corticosterone; Adrenocorticotropic hormone; Glucocorticoid receptor; Hypothalamus; Corticotropin-releasing hormone; Glucocorticoid; Hormone; Mineralocorticoid receptor; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003832271,0.0004911938,0.0008845539,0.0003413257,0.00009634514,0.00004629721,0.0006649988,0.0001360802,0.0001414589],"category_scores_gemma":[0.0002552164,0.0003798934,0.0002450017,0.0006028757,0.0002324706,0.0001877879,0.0002125406,0.0004606408,0.0001076561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001091153,"about_ca_system_score_gemma":0.0000671934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004254742,"about_ca_topic_score_gemma":0.00001623021,"domain_scores_codex":[0.990823,0.005208209,0.00149741,0.001304416,0.0005126937,0.0006542495],"domain_scores_gemma":[0.9965541,0.001418096,0.0009723813,0.0007445629,0.00009699741,0.0002138368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002268314,0.0009463424,0.601238,0.00005706518,0.00005324239,0.001196385,0.00009844079,0.001384652,0.3826845,0.00003324676,0.00006635491,0.009973443],"study_design_scores_gemma":[0.008017448,0.00168927,0.9529749,0.0001450171,0.00011879,0.00006367642,0.00007678893,0.001823027,0.03292359,0.000001203389,0.001746448,0.0004198396],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914636,0.0002649208,0.00004424879,0.0001110369,0.001746237,0.001130645,0.0001114378,0.0002860473,0.004841809],"genre_scores_gemma":[0.997464,0.0008258825,0.00003339721,0.000512563,0.0001322881,0.00003613723,0.00001260299,0.0001570623,0.0008260502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3517369,"threshold_uncertainty_score":0.9998653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06381981695254098,"score_gpt":0.3668386031669429,"score_spread":0.303018786214402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}