{"id":"W2964455242","doi":"10.1101/723254","title":"Evolution of imprinting via lineage-specific insertion of retroviral promoters","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Genomic imprinting; Genetics; Endogenous retrovirus; Germline; Gene; Epigenetics; DNA methylation; Allele; Imprinting (psychology); CRISPR; Transcription (linguistics); Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005966495,0.0004084964,0.0005467518,0.000203011,0.00005096787,0.00003342522,0.0004987573,0.000656381,0.00001266277],"category_scores_gemma":[0.0001439094,0.0004591146,0.0002795874,0.0002427918,0.000149782,0.000008947783,0.0007451467,0.0003676405,0.00001030931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001011212,"about_ca_system_score_gemma":0.0003406232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006586049,"about_ca_topic_score_gemma":8.654761e-7,"domain_scores_codex":[0.9974711,0.0001143018,0.0008393072,0.0008564432,0.0003095048,0.0004093227],"domain_scores_gemma":[0.9970014,0.00001141147,0.0009756489,0.001351567,0.0005586476,0.0001013224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002262788,0.00008857201,0.03501529,0.000553414,0.00009929028,8.775743e-7,0.000005263094,0.0004866484,0.9636462,0.00003927822,0.00002861517,0.00001391026],"study_design_scores_gemma":[0.0003727212,0.0002082266,0.2297427,0.0002571309,0.0000443576,4.254527e-8,0.000004684377,0.0008017668,0.7677245,9.48952e-7,0.0004855434,0.0003574174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773651,0.001485424,0.01963772,0.00001781222,0.0008082353,0.0005869709,0.00005169174,0.00003490301,0.00001208315],"genre_scores_gemma":[0.9921562,0.000223058,0.00715769,0.00001256485,0.0003189855,0.00002953321,0.000001665959,0.00009348802,0.000006811285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1959217,"threshold_uncertainty_score":0.9997861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00872867119547473,"score_gpt":0.2029349845525764,"score_spread":0.1942063133571017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}