{"id":"W2964455242","doi":"10.1101/723254","title":"Evolution of imprinting via lineage-specific insertion of retroviral promoters","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Genomic imprinting; Genetics; Endogenous retrovirus; Germline; Gene; Epigenetics; DNA methylation; Allele; Imprinting (psychology); CRISPR; Transcription (linguistics); Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003261912,0.0002839903,0.0001121249,0.0003611212,0.0001758949,0.0004329213,0.000546196,0.0002454724,0.001036299],"category_scores_gemma":[0.0002257267,0.0002229327,0.000201927,0.0001465271,0.0003316999,0.0002494943,0.0006229803,0.0008143772,0.000494066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281211,"about_ca_system_score_gemma":0.0002372463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003435701,"about_ca_topic_score_gemma":0.0005337246,"domain_scores_codex":[0.9997997,0.00003401919,0.00001892114,0.00005791878,0.00005527681,0.00003416729],"domain_scores_gemma":[0.9997928,0.00004746368,0.0000805189,0.00004086185,0.00001312679,0.00002528356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003737273,0.00001207432,0.001243511,0.00002614038,0.000007128624,0.0001407731,0.00006246406,0.0001804037,0.990019,0.002463976,0.00004915595,0.005758112],"study_design_scores_gemma":[0.00001764966,0.0001212473,0.006346995,0.00002314232,0.00003306422,0.00121236,0.0000597361,0.004529239,0.9697082,0.0008554628,0.01708084,0.00001207456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9316372,0.001562792,0.05760644,0.0002267617,0.00006714567,0.00008001214,0.0004939727,0.0006495144,0.007676248],"genre_scores_gemma":[0.9807222,0.0009092939,0.01285294,0.00006811207,0.00001647262,0.0000386971,0.0005190253,0.0001105262,0.004762657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001036299,"threshold_uncertainty_score":0.003466725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00872867119547473,"score_gpt":0.2029349845525764,"score_spread":0.1942063133571017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}