{"id":"W2964529858","doi":"10.1186/s13063-019-3561-7","title":"Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial","year":2019,"lang":"en","type":"article","venue":"Trials","topic":"Blood transfusion and management","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Health Technology Assessment Programme; National Institute for Health and Care Research","keywords":"Tranexamic acid; Medicine; Placebo; Upper gastrointestinal bleeding; Gastrointestinal bleeding; Randomized controlled trial; Internal medicine; Surgery; Anesthesia; Endoscopy; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04547202,0.004470472,0.01073982,0.00185391,0.0008374142,0.002709152,0.002032317,0.003928635,0.03732569],"category_scores_gemma":[0.05704657,0.001267538,0.01217471,0.002300411,0.002147052,0.003088037,0.001944588,0.006051505,0.003464842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002222137,"about_ca_system_score_gemma":0.003966424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001073053,"about_ca_topic_score_gemma":0.001166667,"domain_scores_codex":[0.9404902,0.0497787,0.002777852,0.002832029,0.002408673,0.001712557],"domain_scores_gemma":[0.9817924,0.009221599,0.003790279,0.002144426,0.00209047,0.0009607971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.9331684,0.0005510399,0.001138776,0.01421322,0.01290026,0.00007444194,0.0001024955,0.001728168,0.0006341608,0.003306462,0.01215568,0.02002701],"study_design_scores_gemma":[0.9296805,0.01341273,0.003166493,0.003806974,0.01679292,0.00006562424,0.000106434,0.008744927,0.0008146521,0.007376095,0.01591502,0.0001176749],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.05366173,0.01894743,0.06702076,0.005140814,0.007604304,0.802809,0.02830679,0.002585615,0.01392364],"genre_scores_gemma":[0.05306052,0.001771112,0.04432685,0.002036867,0.0004886563,0.8912037,0.003318475,0.0001917136,0.003602135],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04547202,"threshold_uncertainty_score":0.2404819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1444680931606097,"score_gpt":0.4194318220384781,"score_spread":0.2749637288778684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}