{"id":"W2964781983","doi":"10.1016/j.jmpt.2018.11.023","title":"Spinal Manipulation Therapy Improves Tactile Allodynia and Peripheral Nerve Functionality and Modulates Blood Oxidative Stress Markers in Rats Exposed to Knee-Joint Immobilization","year":2019,"lang":"en","type":"article","venue":"Journal of Manipulative and Physiological Therapeutics","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Memorial Chiropractic College","funders":"Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul","keywords":"Medicine; Oxidative stress; Sciatic nerve; Allodynia; Anesthesia; Lumbar; Superoxide dismutase; Nitric oxide; Peripheral; Lipid peroxidation; Glutathione peroxidase; Lumbar Spinal Cord; Pharmacology; Internal medicine; Nociception; Hyperalgesia; Surgery; Central nervous system; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009334297,0.000620302,0.0004331723,0.0003866621,0.0001572786,0.0001717758,0.0002079166,0.0003257037,0.001598568],"category_scores_gemma":[0.0001673219,0.0001429999,0.0002767472,0.0001423726,0.0003510711,0.0002530695,0.0001762314,0.000573399,0.0001547849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001328348,"about_ca_system_score_gemma":0.0002791942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005931567,"about_ca_topic_score_gemma":0.001160775,"domain_scores_codex":[0.9998983,0.00001383664,0.000008021464,0.00001861075,0.00002803293,0.00003319285],"domain_scores_gemma":[0.9998797,0.00000855599,0.00006099162,0.00001208809,0.00001377633,0.00002473563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003168757,0.0008214822,0.0007906939,0.0001519379,0.00002499252,0.0001040812,0.00005283671,0.00007361933,0.9865685,0.00003255318,0.00006663865,0.008143991],"study_design_scores_gemma":[0.0004865052,0.06396861,0.05235148,0.00009583004,0.000243223,0.0005091199,0.0004533097,0.001404782,0.8780989,0.0001880941,0.002161032,0.00003896566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977612,0.001109406,0.0006527185,0.00006859643,0.00002874138,0.00002310567,0.00006265804,0.0000359195,0.0002575851],"genre_scores_gemma":[0.9949884,0.001797931,0.001217839,0.00007005986,0.00003048337,0.00008490974,0.0001458127,0.000005743486,0.001658804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001598568,"threshold_uncertainty_score":0.005347729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1582526739395606,"score_gpt":0.3271886420063386,"score_spread":0.168935968066778,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}