{"id":"W2964829801","doi":"10.1016/j.vaccine.2019.07.070","title":"Cricket paralysis virus internal ribosome entry site-derived RNA promotes conventional vaccine efficacy by enhancing a balanced Th1/Th2 response","year":2019,"lang":"en","type":"article","venue":"Vaccine","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"FP7 Information and Communication Technologies; Ministry of Health, British Columbia; Catholic University of Korea","keywords":"Adjuvant; Biology; Immune system; Virology; RNA; Immunogenicity; Interferon; Innate immune system; Immunology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004907027,0.0003652416,0.0007190521,0.0003401419,0.0001299786,0.00005693435,0.0001535386,0.0001648532,0.006015727],"category_scores_gemma":[0.0003788995,0.0002999367,0.000341811,0.000592764,0.00001090601,0.0002156845,0.0001076311,0.0004345806,0.0009735366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001807975,"about_ca_system_score_gemma":0.00009002017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964325,"about_ca_topic_score_gemma":0.00004171071,"domain_scores_codex":[0.9977175,0.0001851321,0.0006670383,0.0005830681,0.0003510384,0.0004962088],"domain_scores_gemma":[0.9984835,0.0002812418,0.00024707,0.0005394571,0.0001898804,0.0002588489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005161917,0.0006507253,0.0806843,0.00007299262,0.0003441956,0.00003566729,0.000166455,0.00002155231,0.9047791,0.00001367012,0.0074918,0.0005775889],"study_design_scores_gemma":[0.01883063,0.002673394,0.4293204,0.0005760844,0.0004954549,0.0001909806,0.0001224008,0.002496994,0.5312079,0.00004598272,0.01337003,0.0006697433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951427,0.0005014901,0.0009574102,0.001645708,0.0004677439,0.0007131321,0.00006111356,0.0002123394,0.0002983675],"genre_scores_gemma":[0.9920439,0.00008212308,0.0002541732,0.0005399548,0.0003108786,0.00004168384,0.0002355977,0.00005694466,0.006434774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3735712,"threshold_uncertainty_score":0.9999453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00874904837449081,"score_gpt":0.2698578667397941,"score_spread":0.2611088183653033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}