{"id":"W2964838955","doi":"10.1136/bmjopen-2018-028752","title":"Bragatston study protocol: a multicentre cohort study on automated quantification of cardiovascular calcifications on radiotherapy planning CT scans for cardiovascular risk prediction in patients with breast cancer","year":2019,"lang":"en","type":"article","venue":"BMJ Open","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Radboud Universitair Medisch Centrum; KWF Kankerbestrijding; Universiteit Utrecht","keywords":"Medicine; Breast cancer; Radiation therapy; Coronary artery disease; Cancer; Radiology; Internal medicine; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001787583,0.000274088,0.0009342227,0.0002329824,0.0001210268,0.00004932545,0.0002139313,0.0000809659,0.0000185899],"category_scores_gemma":[0.00005068771,0.0002245481,0.0003295471,0.0005035995,0.0000263797,0.000194931,0.00002491911,0.000213525,0.000004558877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004670913,"about_ca_system_score_gemma":0.0002300853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002048102,"about_ca_topic_score_gemma":0.00007810757,"domain_scores_codex":[0.9970138,0.0004330477,0.0005841989,0.0007438589,0.0009832436,0.0002418265],"domain_scores_gemma":[0.9978244,0.00006818338,0.0003242819,0.001334387,0.0003669588,0.00008180942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006069717,0.003535103,0.8860581,0.0001403181,0.005537088,0.000003923465,0.001602355,0.09337691,0.0003009134,0.000001615887,0.00005583367,0.003318127],"study_design_scores_gemma":[0.03221752,0.002655639,0.9540531,0.0006883988,0.0009041078,0.000003757471,0.00131669,0.006057479,0.001670905,6.294682e-7,0.0002016548,0.0002300839],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6550395,0.00001014007,0.0004117355,0.00002090172,0.00006205968,0.3441703,0.0001432585,0.00007006867,0.00007205959],"genre_scores_gemma":[0.8174581,0.000002052052,0.0001181959,0.00001969555,0.00005558467,0.1821414,0.0001197395,0.00005600868,0.00002918941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1624186,"threshold_uncertainty_score":0.9156806,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04144199276688006,"score_gpt":0.3808536241835927,"score_spread":0.3394116314167127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}