{"id":"W2965019135","doi":"10.1038/s41379-019-0327-4","title":"“Interchangeability” of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy","year":2019,"lang":"en","type":"review","venue":"Modern Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McMaster University; BC Cancer Agency; McGill University Health Centre; Institut universitaire de cardiologie et de pneumologie de Québec; Dalhousie University; Hamilton Health Sciences; University of Toronto; Saskatchewan Health; University Health Network; Université Laval; University of Saskatchewan; Saskatchewan Health Authority","funders":"National Center for Advancing Translational Sciences","keywords":"Interchangeability; Medicine; Medical physics; Meta-analysis; Data extraction; Diagnostic accuracy; MEDLINE; Grading (engineering); Pathology; Data mining; Computer science; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008890392,0.0005174965,0.008580123,0.0005670517,0.0000193155,0.000004853497,0.0004273173,0.0006816758,0.001271358],"category_scores_gemma":[0.001254438,0.0003741051,0.007344609,0.0006966584,0.0003641888,0.00003095661,0.0001532238,0.0004485631,0.00001624923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000198759,"about_ca_system_score_gemma":0.0003998263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009656215,"about_ca_topic_score_gemma":0.000009128761,"domain_scores_codex":[0.9966489,0.0004098127,0.00159795,0.0007184066,0.0003140546,0.0003108952],"domain_scores_gemma":[0.9938365,0.002571783,0.001413242,0.001900309,0.0002165595,0.00006166811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00045122,0.0005900147,0.00003747444,0.04397086,0.4120016,0.0001305016,0.00059129,0.000003906698,0.002470516,0.000009897714,0.0002000893,0.5395427],"study_design_scores_gemma":[0.0005912971,0.0003413582,0.00006455314,0.001171646,0.8911955,0.0002182885,0.00001880336,0.00003216189,0.0001481375,0.00003859115,0.1058283,0.0003513682],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004876708,0.9965619,0.0004722031,0.00005278004,0.0001476119,0.001046031,0.0007099339,0.00002139204,0.0005004196],"genre_scores_gemma":[0.004271425,0.9935322,0.0001895138,0.00009542937,0.0000345223,0.0002847817,0.0006090867,0.00005780411,0.0009252101],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5391913,"threshold_uncertainty_score":0.9998711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1930581275496032,"score_gpt":0.4155887077541432,"score_spread":0.22253058020454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}