{"id":"W2965168103","doi":"10.1016/j.cub.2019.07.054","title":"Germ Granules Govern Small RNA Inheritance","year":2019,"lang":"en","type":"article","venue":"Current Biology","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institutes of Health; Israel Science Foundation","keywords":"Biology; RNA interference; Genetics; RNA; Mutant; Genomic imprinting; Small RNA; RNA silencing; Germ cell; Germline; Piwi-interacting RNA; Gene silencing; Embryo; Cell biology; Gene; Gene expression; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003018663,0.0003018588,0.0003573762,0.0003247274,0.0003359514,0.001153044,0.0003634224,0.0008444521,0.001088803],"category_scores_gemma":[0.0005887038,0.0002159033,0.0002416525,0.0001225889,0.0007791329,0.001051088,0.0004478193,0.0007017119,0.0006192334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004650696,"about_ca_system_score_gemma":0.0002264799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003717361,"about_ca_topic_score_gemma":0.0005150646,"domain_scores_codex":[0.9998378,0.00002595701,0.00001022537,0.00005200978,0.00004667598,0.00002733052],"domain_scores_gemma":[0.9993881,0.0001439841,0.0001599227,0.00009151975,0.00006276883,0.0001537415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001668712,0.00001040944,0.0007448766,0.00003808187,0.000006216304,0.0001692135,0.00004792324,0.000193492,0.9862928,0.00779875,0.0002787582,0.004252607],"study_design_scores_gemma":[0.00007625917,0.0001745928,0.01495272,0.00003205367,0.00003619211,0.0007970402,0.0001242573,0.009459284,0.9504975,0.01235695,0.01144987,0.00004336407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9446122,0.004504114,0.04098048,0.0006474049,0.0003119285,0.00002954954,0.0002897614,0.001125504,0.007499107],"genre_scores_gemma":[0.9920148,0.0006640559,0.004567614,0.0000892142,0.00004727095,0.00001012213,0.0001212518,0.00008720143,0.002398392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001153044,"threshold_uncertainty_score":0.00364238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741393084700431,"score_gpt":0.2545166778727433,"score_spread":0.237102747025739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}