{"id":"W2965206207","doi":"10.3390/cancers11081069","title":"Liquid Biopsy in Lung Cancer Screening: The Contribution of Metabolomics. Results of A Pilot Study","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; University of Manitoba; CancerCare Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba","keywords":"Lung cancer; Metabolomics; Medicine; Cancer; Metabolite; Internal medicine; Oncology; Pathology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002243652,0.00007184402,0.0001568192,0.000029462,0.00001670714,0.000002398774,0.0001697521,0.00002817372,0.000005913129],"category_scores_gemma":[0.00004436106,0.00005443529,0.00003245534,0.000162867,0.00006013904,0.000002384288,0.00005091264,0.00004805826,4.868909e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002754017,"about_ca_system_score_gemma":0.0001828377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002062574,"about_ca_topic_score_gemma":0.0004499509,"domain_scores_codex":[0.9993573,0.00004353711,0.000232751,0.0001744213,0.00007395368,0.0001180127],"domain_scores_gemma":[0.9994237,0.00001316045,0.0001524084,0.0003111801,0.00007885348,0.00002064156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001055132,0.00006250963,0.01271594,0.000007908489,0.00007166458,1.12377e-7,0.0001096844,0.00122782,0.9839886,0.0002098078,0.0002606394,0.0002902105],"study_design_scores_gemma":[0.005572875,0.00129617,0.09947654,0.00003866155,0.000121468,8.923762e-7,0.0006600093,0.0006344293,0.8789856,0.00001281184,0.01298763,0.000212913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956151,0.003147842,0.0002009873,0.0001005581,0.00009468359,0.0004968694,0.0001422555,0.0000023172,0.0001993674],"genre_scores_gemma":[0.9993214,0.0002894386,0.00004056064,0.00004077683,0.00005574286,0.00008555035,0.00003960113,0.000006599076,0.0001203531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.105003,"threshold_uncertainty_score":0.3118009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379907881879853,"score_gpt":0.2904780747880298,"score_spread":0.2766789959692312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}