{"id":"W2965452705","doi":"10.1016/j.biopsych.2019.07.018","title":"Neuronal Autophagy in Synaptic Functions and Psychiatric Disorders","year":2019,"lang":"en","type":"review","venue":"Biological Psychiatry","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institutes of Health; Stanley Foundation; National Center for Research Resources; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Defense","keywords":"Autophagy; Neuroscience; Synaptic plasticity; Biology; Homeostasis; Synapse; Homeostatic plasticity; Synaptic scaling; Organelle; Metaplasticity; Cell biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000588256,0.001213594,0.002094768,0.002744788,0.0003517941,0.001538767,0.0009246098,0.001682235,0.004621415],"category_scores_gemma":[0.0007713682,0.0003149312,0.0005054376,0.002806859,0.0006456767,0.00128604,0.001169972,0.002076013,0.002039424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008048743,"about_ca_system_score_gemma":0.001482231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001379752,"about_ca_topic_score_gemma":0.003651636,"domain_scores_codex":[0.9998208,0.00003188878,0.00003054694,0.00002940378,0.00006401568,0.00002350475],"domain_scores_gemma":[0.999737,0.0001188254,0.00003954229,0.000009618808,0.00006149462,0.00003350686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001459073,0.00006291475,0.0001269001,0.01830544,0.0001300391,0.0001995566,0.00004658706,0.0004449253,0.0009282406,0.003577968,0.05420464,0.9218269],"study_design_scores_gemma":[0.00004920039,0.00007643771,0.0007176534,0.007270691,0.0002642795,0.0008810349,0.00007268268,0.0001336388,0.0002155614,0.004177734,0.9861146,0.00002649291],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004846083,0.9985293,0.00006344254,0.0002318623,0.0002577369,0.000002674744,0.00001783387,0.000006455777,0.0008422905],"genre_scores_gemma":[0.0004341313,0.9983051,0.0001219409,0.000240999,0.0003153927,0.000005021776,0.00002788239,0.000001228349,0.0005484311],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004621415,"threshold_uncertainty_score":0.01546019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04916489222027164,"score_gpt":0.3396567615266631,"score_spread":0.2904918693063914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}