{"id":"W2965458248","doi":"10.3390/cancers11081119","title":"NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"FOXM1; Anaplastic lymphoma kinase; Cancer research; Thiostrepton; Anaplastic large-cell lymphoma; Biology; Carcinogenesis; Cell culture; Cell cycle; Cell; Molecular biology; Lymphoma; Cancer; Gene; Medicine; RNA; Immunology; Oncology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009368111,0.0001872606,0.000128746,0.0001821819,0.0001933704,0.0001661439,0.0001473542,0.0002163732,0.001226045],"category_scores_gemma":[0.00008178195,0.0000842701,0.0001799673,0.0001096944,0.0001377282,0.0001477212,0.0001773936,0.0002319587,0.0003354248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004166293,"about_ca_system_score_gemma":0.0001975401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006902658,"about_ca_topic_score_gemma":0.001064588,"domain_scores_codex":[0.9999218,0.000007479763,0.000004240203,0.00001925679,0.00003415823,0.00001296415],"domain_scores_gemma":[0.9999677,0.000003701816,0.00001119461,0.00000245283,0.000006434561,0.000008455975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007038237,0.00001382137,0.003691935,0.00006189037,0.000006520423,0.0003076836,0.00001978892,0.00009769519,0.9907397,0.0002496733,0.0001652859,0.00457562],"study_design_scores_gemma":[0.00002072288,0.0001550279,0.05289879,0.00001610594,0.00004708145,0.002831524,0.0000621,0.002861182,0.921464,0.0002819329,0.01935319,0.000008269843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857442,0.006260009,0.004684307,0.0002595148,0.0000393388,0.00002683479,0.000349335,0.00009615291,0.002540275],"genre_scores_gemma":[0.9942393,0.001105462,0.001380053,0.00006114625,0.00001148819,0.00001468301,0.0003522901,0.000008764599,0.002826745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001226045,"threshold_uncertainty_score":0.004101515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00388486121936193,"score_gpt":0.2041458837218915,"score_spread":0.2002610225025296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}