{"id":"W2966151337","doi":"10.3390/cancers11081128","title":"CSCs in Breast Cancer—One Size Does Not Fit All: Therapeutic Advances in Targeting Heterogeneous Epithelial and Mesenchymal CSCs","year":2019,"lang":"en","type":"review","venue":"Cancers","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"CD44; Cancer stem cell; Breast cancer; Cancer research; Triple-negative breast cancer; CD24; Cancer; Population; Medicine; Oncology; Bioinformatics; Biology; Internal medicine; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003658238,0.0005760784,0.0009228513,0.0017147,0.0002231111,0.0007965167,0.0005397983,0.0007415858,0.002639018],"category_scores_gemma":[0.0004239292,0.0001742266,0.0004090518,0.001670684,0.000324776,0.001050976,0.0005639505,0.001498454,0.001197032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005349625,"about_ca_system_score_gemma":0.0009859904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009125894,"about_ca_topic_score_gemma":0.001717118,"domain_scores_codex":[0.9998997,0.00001652335,0.00001361764,0.00001730744,0.00004070721,0.00001206252],"domain_scores_gemma":[0.9998461,0.00006763128,0.00001749016,0.000005205952,0.00004704076,0.00001648724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000589234,0.00005482631,0.0001502472,0.01654962,0.00006558334,0.0001509058,0.00007236486,0.0003563789,0.002100584,0.005559617,0.03185236,0.9430287],"study_design_scores_gemma":[0.00001277948,0.0001006844,0.0007464847,0.00400559,0.00008783321,0.001091925,0.00007986809,0.0001074636,0.0003988679,0.002814841,0.9905378,0.00001592053],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000138949,0.9983196,0.0001077603,0.0003887677,0.0002076921,0.000003387122,0.0000171717,0.000007531115,0.0008092158],"genre_scores_gemma":[0.0005144663,0.9987221,0.0001058612,0.0001669752,0.00008903035,0.000003255905,0.00001842272,0.000001052079,0.0003788446],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002639018,"threshold_uncertainty_score":0.008828402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04999604767104612,"score_gpt":0.3506553409275194,"score_spread":0.3006592932564732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}