{"id":"W2966220408","doi":"10.1038/s41467-019-11169-x","title":"Hydrogen peroxide release by bacteria suppresses inflammasome-dependent innate immunity","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Umeå Universitet; School of Medicine, New York University; Vetenskapsrådet; Cancerfonden; Rijksuniversiteit Groningen; Stockholms Universitet; York University","keywords":"Inflammasome; Innate immune system; Immune system; Bacteria; Microbiology; Biology; Immunity; Hydrogen peroxide; Streptococcus pneumoniae; Pathogen; Immunology; Inflammation; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002182572,0.0003381659,0.000311882,0.0001408022,0.0001068155,0.000289195,0.0001165529,0.0003204205,0.001780702],"category_scores_gemma":[0.0002315413,0.0001076976,0.0001980633,0.00007966572,0.0002683245,0.0001861734,0.0003109305,0.0005361724,0.0003328235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001280234,"about_ca_system_score_gemma":0.0001885064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001756742,"about_ca_topic_score_gemma":0.0001751716,"domain_scores_codex":[0.999801,0.00005702297,0.00002032916,0.00001912796,0.00005109362,0.00005137525],"domain_scores_gemma":[0.9998807,0.00003103121,0.00003093045,0.00001546192,0.00001147315,0.00003054755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004204036,0.00005479056,0.000113504,0.00006317088,0.000005984215,0.00004672076,0.000007232137,0.00003344275,0.9979261,0.00006696033,0.00007240546,0.001189184],"study_design_scores_gemma":[0.00009311579,0.001667713,0.002268368,0.00001694906,0.00001249846,0.0001864527,0.00003095448,0.0005770435,0.9930283,0.000171787,0.001942079,0.000004608144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888387,0.00561103,0.002651426,0.0003454568,0.0002219673,0.00003387792,0.0002003335,0.0001164868,0.001980843],"genre_scores_gemma":[0.9962686,0.00092372,0.001022244,0.00009451831,0.00004382053,0.00002537367,0.0001141454,0.000008240878,0.001499278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001780702,"threshold_uncertainty_score":0.005957007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005067008187001367,"score_gpt":0.2423042855975623,"score_spread":0.2372372774105609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}