{"id":"W2966333491","doi":"10.1093/jn/nxz154","title":"Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions","year":2019,"lang":"en","type":"review","venue":"Journal of Nutrition","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":279,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University of Guelph","funders":"University of Guelph","keywords":"Gut microbiome; Microbiome; State (computer science); Regulatory science; Biology; Computational biology; Bioinformatics; Computer science; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004783086,0.001164955,0.00319121,0.001982344,0.000482638,0.003394552,0.001680354,0.003691835,0.003040508],"category_scores_gemma":[0.006402247,0.000385173,0.0005460711,0.002582934,0.00256767,0.00440981,0.002051232,0.004710634,0.001436272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001715124,"about_ca_system_score_gemma":0.004634744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002124972,"about_ca_topic_score_gemma":0.003420247,"domain_scores_codex":[0.9990892,0.0002151883,0.0001230321,0.0001667929,0.0003149585,0.00009087582],"domain_scores_gemma":[0.99428,0.003567546,0.0005285309,0.000124273,0.001033623,0.0004660189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001755923,0.00005251918,0.0003858206,0.02077675,0.000114761,0.0001234585,0.00009218608,0.0003308187,0.001424282,0.01639702,0.03697702,0.9231498],"study_design_scores_gemma":[0.00002449405,0.00008448846,0.001192192,0.01509078,0.0001872674,0.0005858253,0.0002175613,0.0001783295,0.0004773665,0.01417121,0.967741,0.00004948495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003315985,0.9981279,0.0001066873,0.001187285,0.0003281582,0.000001393093,0.000009887441,0.000002938148,0.0002025333],"genre_scores_gemma":[0.0003598974,0.9982812,0.0002138721,0.0005985318,0.0004254264,0.000003072137,0.00001659205,0.000001164703,0.0001002089],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004783086,"threshold_uncertainty_score":0.02529562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02751009181845814,"score_gpt":0.3252794120342394,"score_spread":0.2977693202157812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}