{"id":"W2966395428","doi":"10.3390/molecules24152746","title":"A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Bioactive natural compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Australian Research Council; Vetenskapsrådet; Swedish Institute; University of Dar es Salaam","keywords":"Sesquiterpene; Cytotoxic T cell; Chemistry; Stereochemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004254425,0.000360972,0.0002437413,0.000505253,0.0002605166,0.0001903284,0.0001313952,0.0002114013,0.001002023],"category_scores_gemma":[0.0000745509,0.00008566221,0.0001363266,0.0002789432,0.000147787,0.0002661282,0.0001935358,0.0002554345,0.0001979089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001476759,"about_ca_system_score_gemma":0.0002073451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007137399,"about_ca_topic_score_gemma":0.0019039,"domain_scores_codex":[0.9999723,0.000003416271,0.000003357068,0.000007231019,0.000006813961,0.000006896787],"domain_scores_gemma":[0.9999635,0.000005255061,0.00000785371,0.000003484411,0.000008070576,0.00001178739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001453898,0.00003725713,0.0005811413,0.0003050714,0.000009802752,0.0003777975,0.0000636242,0.0001563361,0.988134,0.000155931,0.00007669035,0.009957048],"study_design_scores_gemma":[0.0001397757,0.001089816,0.09584839,0.0001023068,0.0001202098,0.003384809,0.0002893708,0.001017878,0.8697881,0.0005977466,0.02755176,0.00006996237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795184,0.009504343,0.002641174,0.0002007287,0.00003186928,0.00008161819,0.001480817,0.00009300515,0.006448054],"genre_scores_gemma":[0.9918666,0.00235943,0.00222933,0.0001070551,0.000016659,0.00002655637,0.0009859392,0.000008764546,0.002399542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001002023,"threshold_uncertainty_score":0.003352046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005927315410722608,"score_gpt":0.2245723333656336,"score_spread":0.218645017954911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}