{"id":"W2966395428","doi":"10.3390/molecules24152746","title":"A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Bioactive natural compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Australian Research Council; Vetenskapsrådet; Swedish Institute; University of Dar es Salaam","keywords":"Sesquiterpene; Cytotoxic T cell; Chemistry; Stereochemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005765667,0.0002258754,0.0002249734,0.00005064052,0.00004978169,0.00007498852,0.0001485523,0.0002183769,0.00005257548],"category_scores_gemma":[0.00002617411,0.0002017344,0.00005853731,0.00006276917,0.00008727014,0.00000989112,0.0001972328,0.0001334328,0.00002313263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008281863,"about_ca_system_score_gemma":0.00003799771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004154633,"about_ca_topic_score_gemma":0.00009755608,"domain_scores_codex":[0.9989369,0.00004211421,0.0001465305,0.0005090397,0.0001272693,0.0002381352],"domain_scores_gemma":[0.9994907,0.00002147313,0.00006632211,0.0002780844,0.00003253062,0.0001109035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001600241,0.00001355631,0.01040471,0.000009730802,0.00007371521,0.000002985334,0.00004200857,0.000001173901,0.9866763,0.0003633799,0.0005360971,0.001716365],"study_design_scores_gemma":[0.001533197,0.0002170652,0.06744199,0.00002186529,0.00005541463,0.00003172102,0.0000347458,0.00007273803,0.8795382,0.0007384146,0.04989902,0.000415589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912559,0.006943591,0.0003925952,0.000151655,0.0001300697,0.0002204237,0.00007724192,0.00001898082,0.0008095233],"genre_scores_gemma":[0.9951468,0.00009530892,0.002899058,0.0008542509,0.0002366539,0.000005830842,0.00005428356,0.00003541535,0.0006723931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.107138,"threshold_uncertainty_score":0.8226489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005927315410722608,"score_gpt":0.2245723333656336,"score_spread":0.218645017954911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}