{"id":"W2966531101","doi":"10.1016/j.ijpharm.2019.118573","title":"Treatment of endotoxin-induced uveitis by topical application of cyclosporine a-loaded PolyGel™ in rabbit eyes","year":2019,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Deanship of Scientific Research, King Saud University; King Saud University","keywords":"In vivo; Pharmacology; Cmax; Pharmacokinetics; Uveitis; Chemistry; Ethylene glycol; Caprolactone; Ex vivo; Toxicity; Medicine; In vitro; Immunology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003115646,0.0004541893,0.0004942107,0.0002349122,0.000267859,0.000249392,0.0002388416,0.0004449565,0.001021222],"category_scores_gemma":[0.000238263,0.000243151,0.0005825381,0.0001821926,0.0004421038,0.0002949388,0.00015124,0.0008264887,0.0003083463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001942904,"about_ca_system_score_gemma":0.0003642788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007459095,"about_ca_topic_score_gemma":0.0008965001,"domain_scores_codex":[0.9997821,0.0000361088,0.00002566822,0.00003319989,0.00003807127,0.0000849691],"domain_scores_gemma":[0.9998121,0.00005095506,0.00004332475,0.00002800806,0.00001921589,0.00004642937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001442373,0.0002342135,0.0001387833,0.00008013792,0.00001125357,0.0001263206,0.00004446129,0.00007668855,0.9959413,0.00007511352,0.0000548371,0.001774491],"study_design_scores_gemma":[0.0001033765,0.004309188,0.00188199,0.000009047066,0.0000409438,0.0001711171,0.00003975037,0.0006330581,0.9920396,0.00003282311,0.0007312795,0.000007886326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959259,0.001800052,0.001129894,0.0001022858,0.000176127,0.00003854744,0.00008786147,0.00004788275,0.0006914987],"genre_scores_gemma":[0.9955369,0.0014187,0.001342864,0.00004164612,0.00006816543,0.00003933924,0.0001141596,0.00001070974,0.001427605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001021222,"threshold_uncertainty_score":0.003416359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02236705890915897,"score_gpt":0.35127846015199,"score_spread":0.3289114012428311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}