{"id":"W2966593825","doi":"10.1038/s41562-019-0659-6","title":"Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders","year":2019,"lang":"en","type":"article","venue":"Nature Human Behaviour","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Mental Health; National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Deutsche Forschungsgemeinschaft; Novartis Pharmaceuticals Corporation; MQ: Transforming Mental Health; Northern California Institute for Research and Education; BioClinica; Biogen; Pfizer; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; McDonnell Center for Systems Neuroscience; F. Hoffmann-La Roche; University of Southern California; National Alliance for Research on Schizophrenia and Depression; U.S. Department of Defense; Eli Lilly and Company; Bristol-Myers Squibb; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Connectome; Vulnerability (computing); Psychiatry; Psychology; Neuroscience; Functional connectivity; Medicine; Computer science; Computer security","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256822,0.0002038505,0.0003132093,0.00004942838,0.0002642239,0.00004891909,0.00008812444,0.0003600155,0.0002335905],"category_scores_gemma":[0.0001186567,0.0001496814,0.0001871194,0.0001247225,0.00007572178,0.00007175788,0.00004936115,0.0006116474,0.00001419556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001247625,"about_ca_system_score_gemma":0.00001323889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000101558,"about_ca_topic_score_gemma":0.00007170457,"domain_scores_codex":[0.9986878,0.00005254515,0.0002112576,0.0005801848,0.000157412,0.0003108206],"domain_scores_gemma":[0.9992908,0.0001544196,0.0000606148,0.0003012461,0.00005895719,0.0001340013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002466236,0.0008050729,0.9933893,0.00003837691,0.00002550295,0.000009301172,0.00006139293,0.000001312418,0.000549658,0.001853532,0.002227661,0.0007922761],"study_design_scores_gemma":[0.00467626,0.002359129,0.9848586,0.000004572121,0.00009018928,0.000008844322,0.00001855551,0.0000575518,0.00001142008,0.006894004,0.0008705233,0.0001502942],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990496,0.0003440113,0.00001496539,0.006906124,0.0002098666,0.001515588,0.0001552012,0.00009502408,0.000263185],"genre_scores_gemma":[0.9936129,0.000006903254,0.0002054013,0.005194201,0.00007102703,0.0001179025,0.0002229728,0.00002195355,0.0005467077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008530633,"threshold_uncertainty_score":0.6103829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01730522079657961,"score_gpt":0.3483445865225699,"score_spread":0.3310393657259903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}