{"id":"W2966640019","doi":"10.1002/ajmg.c.31730","title":"The diagnostic workup in a patient with AMC: Overview of the clinical evaluation and paraclinical analyses with review of the literature","year":2019,"lang":"en","type":"review","venue":"American Journal of Medical Genetics Part C Seminars in Medical Genetics","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"Arthrogryposis multiplex congenita; Muscle contracture; Medicine; Anterior Horn Cell; Arthrogryposis; Physical medicine and rehabilitation; Bioinformatics; Pathology; Surgery; Disease; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.009815333,0.0005017455,0.003512817,0.00017528,0.00005983765,0.0000212826,0.001579321,0.0005084494,0.00008090536],"category_scores_gemma":[0.01984089,0.0001970516,0.0008424226,0.002346079,0.004036234,0.00001437009,0.0005583557,0.003556647,9.931024e-7],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007662184,"about_ca_system_score_gemma":0.006767595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006895504,"about_ca_topic_score_gemma":0.00004680674,"domain_scores_codex":[0.9818341,0.005148458,0.003973125,0.0005273728,0.007990828,0.000526125],"domain_scores_gemma":[0.9860728,0.0080269,0.002987371,0.001384846,0.0008162023,0.0007119041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001233523,0.0004679357,0.009987351,0.01195207,0.0004114577,0.0002010609,0.0001081981,0.00001082273,1.208081e-7,0.000002795956,0.0006657381,0.9760691],"study_design_scores_gemma":[0.002377452,0.004787017,0.006266463,0.6290047,0.0047609,0.002404339,0.0002849813,0.0002307852,0.00000395819,0.00002400961,0.3495494,0.0003060234],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0287767,0.965705,0.00001541809,0.002980791,0.0003288322,0.002151198,0.00001030068,0.000001545965,0.0000302562],"genre_scores_gemma":[0.00303506,0.9948695,0.0003545124,0.001428666,0.0001693199,0.00006382755,0.000008287773,0.00005691508,0.00001387332],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9757631,"threshold_uncertainty_score":0.9988631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1309413689522941,"score_gpt":0.5124764044890071,"score_spread":0.381535035536713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}