{"id":"W2966674500","doi":"10.1172/jci128865","title":"Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust; Medical Research Council; Bill and Melinda Gates Foundation","keywords":"Immunology; Innate immune system; Colonization; Immune system; Acquired immune system; Streptococcus pneumoniae; Microbiology; Pneumococcal infections; Biology; Medicine; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003535545,0.0003022299,0.0004512263,0.0002005485,0.0001852277,0.000248206,0.0001082923,0.0004035683,0.001458362],"category_scores_gemma":[0.0004097658,0.0001586896,0.0002120634,0.0000838129,0.0003821383,0.0001958578,0.0002321346,0.0008623974,0.0001908736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002118979,"about_ca_system_score_gemma":0.0002037578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000312178,"about_ca_topic_score_gemma":0.0005804991,"domain_scores_codex":[0.999712,0.00007523191,0.00001899226,0.00005016326,0.0000599654,0.00008363419],"domain_scores_gemma":[0.9998254,0.00004384791,0.00002729801,0.00002425237,0.00001923773,0.00005997661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004187748,0.0007230319,0.003862171,0.00007038042,0.00001465075,0.0004800033,0.0001352328,0.00006925968,0.9870559,0.0000446594,0.00006618788,0.003290717],"study_design_scores_gemma":[0.0004255622,0.05075317,0.2373924,0.00005240021,0.00008742222,0.00398264,0.000711824,0.001921879,0.7024333,0.0002217915,0.001989043,0.00002861006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992397,0.0002217512,0.0001390145,0.00002194429,0.0000157964,0.0000295586,0.00005456531,0.000008221091,0.0002694668],"genre_scores_gemma":[0.9987773,0.000155274,0.0002370123,0.00006442505,0.00001464595,0.00005285267,0.0001998455,0.000003158363,0.0004954686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458362,"threshold_uncertainty_score":0.004878759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0726633202950458,"score_gpt":0.4028023871286754,"score_spread":0.3301390668336296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}