{"id":"W2966786916","doi":"10.1007/s10863-019-09807-6","title":"Increased reactive oxygen species production and maintenance of membrane potential in VDAC-less Neurospora crassa mitochondria","year":2019,"lang":"en","type":"article","venue":"Journal of Bioenergetics and Biomembranes","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; University of Alberta","keywords":"Voltage-dependent anion channel; Neurospora crassa; Mitochondrion; Biochemistry; Biology; Alternative oxidase; Oxidative phosphorylation; Hexokinase; Reactive oxygen species; Membrane potential; Succinate dehydrogenase; Cell biology; Glycolysis; Bacterial outer membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207467,0.0003173641,0.0003490239,0.0001802523,0.0002401464,0.0005830047,0.0004288527,0.0004930269,0.001624965],"category_scores_gemma":[0.0002656844,0.0001793244,0.0002693076,0.0001914158,0.0004152125,0.0003451848,0.000317543,0.0009140839,0.0002772631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005557752,"about_ca_system_score_gemma":0.0003864817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004102334,"about_ca_topic_score_gemma":0.00220987,"domain_scores_codex":[0.9997942,0.00001851247,0.00002474272,0.00006074979,0.00005804902,0.00004369414],"domain_scores_gemma":[0.9996313,0.00004095168,0.00007517311,0.00008481453,0.00005571457,0.0001119585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000143597,0.00001147464,0.000143696,0.00001298832,0.000003878456,0.00003055805,0.00001229118,0.00001556797,0.9993597,0.00004768752,0.00001375982,0.000204807],"study_design_scores_gemma":[0.00002034072,0.00009043825,0.00797656,0.00000357432,0.00001377183,0.0002120332,0.00009152001,0.0006152153,0.9902737,0.00006200248,0.0006337466,0.000007151004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979392,0.0002717667,0.0009372311,0.0001242562,0.00003649242,0.000007232369,0.0003540944,0.00004614561,0.0002835447],"genre_scores_gemma":[0.9979659,0.00008677781,0.0004959697,0.00003406448,0.000003828163,0.000006518044,0.0003423277,0.0000151724,0.00104957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004102334,"threshold_uncertainty_score":0.008156955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007630432718986523,"score_gpt":0.2090822581986983,"score_spread":0.2014518254797118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}