{"id":"W2966804906","doi":"10.1039/c9sc02507c","title":"Catalyst-controlled regiodivergent ring-opening C(sp<sup>3</sup>)–Si bond-forming reactions of 2-arylaziridines with silylborane enabled by synergistic palladium/copper dual catalysis","year":2019,"lang":"en","type":"article","venue":"Chemical Science","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Ministère de l'Économie, de la Science et de l'Innovation - Québec","keywords":"Phenethylamines; Regioselectivity; Stereospecificity; Chemistry; Catalysis; Silylation; Structural isomer; Palladium; Ring (chemistry); Tandem; Coupling reaction; Combinatorial chemistry; Reaction conditions; Medicinal chemistry; Stereochemistry; Organic chemistry; Materials science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005237479,0.000370271,0.0007723882,0.0001549828,0.0003362933,0.0001255174,0.0007535726,0.0001489351,0.000780931],"category_scores_gemma":[0.000738693,0.0002814216,0.0002440784,0.001026172,0.0007004423,0.0005499926,0.0002015659,0.0002989992,0.0001075379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003223237,"about_ca_system_score_gemma":0.0003048188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005706554,"about_ca_topic_score_gemma":0.000007735028,"domain_scores_codex":[0.9966337,0.00001135331,0.00069964,0.0009132102,0.001014707,0.0007273806],"domain_scores_gemma":[0.9974965,0.0004231866,0.000426007,0.0009888669,0.0002902652,0.0003752176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001666586,0.0001616812,0.001261206,0.0001014489,0.0001124073,0.000007634639,0.0002306512,0.0003815165,0.9963651,0.0001146013,0.0008021482,0.0002949563],"study_design_scores_gemma":[0.001779924,0.00002261576,0.00004368987,0.0001993895,0.0002696656,0.00005350836,0.001011362,0.0034078,0.9896289,0.00002123256,0.003128132,0.000433822],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9709455,0.0001969257,0.00003940196,0.0002611083,0.0000681345,0.0002102057,0.00003977483,0.00008828298,0.02815068],"genre_scores_gemma":[0.9962004,0.00003358232,0.0002886356,0.00002852763,0.00009685242,0.00007979973,0.00009487619,0.00003009686,0.00314717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02525498,"threshold_uncertainty_score":0.9999638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009293386512873807,"score_gpt":0.2195288069423785,"score_spread":0.2102354204295047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}