{"id":"W2966872618","doi":"10.1016/j.bbmt.2019.07.036","title":"Recombinant Zoster Vaccine Significantly Reduces the Impact on Quality of Life Caused by Herpes Zoster in Adult Autologous Hematopoietic Stem Cell Transplant Recipients: A Randomized Placebo-Controlled Trial (ZOE-HSCT)","year":2019,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency","funders":"Basilea Pharmaceutica; Shire; Sanofi; Pharmaceuticals Bayer; GlaxoSmithKline; Genzyme; Pfizer","keywords":"Medicine; Placebo; Quality of life (healthcare); Confidence interval; Randomized controlled trial; Adverse effect; Rash; Internal medicine; Hematopoietic stem cell transplantation; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001116687,0.0008099211,0.001989316,0.0003140736,0.0002559354,0.0006810653,0.0004428417,0.001141139,0.003531536],"category_scores_gemma":[0.001007879,0.0002909997,0.001347953,0.0002612725,0.0005768313,0.0003906603,0.0002277917,0.001399721,0.0002646016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003190986,"about_ca_system_score_gemma":0.0004839217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005126331,"about_ca_topic_score_gemma":0.0009458637,"domain_scores_codex":[0.9996079,0.0002148769,0.00003449255,0.00005173162,0.00003683269,0.00005429975],"domain_scores_gemma":[0.9995975,0.0001290403,0.0001154818,0.00002548765,0.00002639349,0.0001062301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9633496,0.006187466,0.0008390292,0.0009987712,0.001246741,0.00003621253,0.00003259459,0.0001982192,0.003317068,0.00006234615,0.0003745192,0.02335743],"study_design_scores_gemma":[0.8862542,0.1074389,0.004229237,0.00005431696,0.0006933576,0.00003587479,0.00001993118,0.0002810748,0.0005443875,0.00006356203,0.0003759494,0.000009133727],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902557,0.007045212,0.0002190672,0.0003224016,0.0003200372,0.001000454,0.0002965427,0.00004654815,0.000494106],"genre_scores_gemma":[0.9919875,0.003656776,0.0006529287,0.0005502845,0.000419424,0.001544753,0.0003455445,0.000006651042,0.0008361636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003531536,"threshold_uncertainty_score":0.01181418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01144504952548733,"score_gpt":0.2743426254026436,"score_spread":0.2628975758771563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}