{"id":"W2966885713","doi":"10.3390/cancers11081150","title":"Association between PD-1 and PD-L1 Polymorphisms and the Risk of Cancer: A Meta-Analysis of Case-Control Studies","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach; Research Manitoba","keywords":"Odds ratio; Internal medicine; Meta-analysis; Medicine; Allele; Gastroenterology; Case-control study; Genetic model; Cancer; Genotype; Programmed cell death 1; Confidence interval; Oncology; PD-L1; Gene; Genetics; Biology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008493943,0.0001229686,0.001275153,0.0001248685,0.00005117443,0.000006215563,0.00004362095,0.00006369298,0.0001537127],"category_scores_gemma":[0.00008708295,0.00007089231,0.0004806832,0.0003838708,0.0002303152,0.00003957915,0.00001640755,0.0000935923,2.843616e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004108481,"about_ca_system_score_gemma":0.0001313695,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01506183,"about_ca_topic_score_gemma":0.002652222,"domain_scores_codex":[0.9989891,0.0001354958,0.0003409326,0.0001851768,0.0002181575,0.0001311365],"domain_scores_gemma":[0.9983672,0.0007018991,0.0005394517,0.0002176922,0.0001383599,0.00003540452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001632705,0.000004505051,0.4157673,0.00008225421,0.5760921,0.000003138253,0.001963805,0.0001153446,0.0007035386,0.0000153755,0.000316719,0.00330324],"study_design_scores_gemma":[0.008219086,0.0002027209,0.2848386,0.00002856925,0.7024263,0.000005850934,0.001625604,0.0005256329,0.001248247,0.00004123563,0.000705583,0.0001325065],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8641278,0.1334303,0.000009725775,0.001444768,0.00007165722,0.0004201168,0.0003789842,0.000006085396,0.0001105217],"genre_scores_gemma":[0.9887412,0.01014609,0.0000229179,0.0003156492,0.00003984946,0.00004506815,0.000003180072,0.000008290772,0.0006777768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1309287,"threshold_uncertainty_score":0.991497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03468073863171975,"score_gpt":0.3128203849200629,"score_spread":0.2781396462883431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}