{"id":"W2966885713","doi":"10.3390/cancers11081150","title":"Association between PD-1 and PD-L1 Polymorphisms and the Risk of Cancer: A Meta-Analysis of Case-Control Studies","year":2019,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Institute in Oncology and Hematology; CancerCare Manitoba","funders":"Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach; Research Manitoba","keywords":"Odds ratio; Internal medicine; Meta-analysis; Medicine; Allele; Gastroenterology; Case-control study; Genetic model; Cancer; Genotype; Programmed cell death 1; Confidence interval; Oncology; PD-L1; Gene; Genetics; Biology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01186762,0.002694624,0.01124103,0.003656454,0.0007122872,0.002890843,0.001707865,0.001754183,0.00180671],"category_scores_gemma":[0.02167162,0.001697565,0.03297852,0.006376394,0.0005309266,0.001014935,0.001088159,0.001980487,0.0001845974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001338835,"about_ca_system_score_gemma":0.001121668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005216999,"about_ca_topic_score_gemma":0.006709686,"domain_scores_codex":[0.9910519,0.004260225,0.001840758,0.001778731,0.0007568762,0.000311563],"domain_scores_gemma":[0.9866117,0.009635523,0.001644571,0.001050432,0.0008526856,0.0002050142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.005335271,0.00004752333,0.03800739,0.02023885,0.925988,0.0002838686,0.00005022567,0.001276342,0.0005496852,0.0001042803,0.0004801781,0.007638514],"study_design_scores_gemma":[0.0006459579,0.0002064743,0.01627689,0.001072438,0.979845,0.0001766825,0.00002221259,0.0006610503,0.0001690809,0.0002210362,0.0006819778,0.00002112759],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.07098033,0.9229814,0.003328014,0.0003683527,0.00035121,0.0002200657,0.00124925,0.00007793628,0.0004434304],"genre_scores_gemma":[0.7314039,0.258791,0.004937037,0.0009998797,0.0005205309,0.0006829474,0.002036645,0.00007533303,0.0005528007],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01186762,"threshold_uncertainty_score":0.06276268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03468073863171975,"score_gpt":0.3128203849200629,"score_spread":0.2781396462883431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}