{"id":"W2966997102","doi":"10.1038/s41589-019-0336-0","title":"Mycobacterium tuberculosis releases an antacid that remodels phagosomes","year":2019,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Phagosome; Phagolysosome; Microbiology; Macrophage; Intracellular; Bacteria; Virulence; Biology; Foam cell; Phagocytosis; Chemistry; Pathogen; Cell biology; Gene; Biochemistry; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002689553,0.0002229907,0.0002157523,0.0002617627,0.0002563958,0.0004581585,0.0002151526,0.001077442,0.001330887],"category_scores_gemma":[0.0004820941,0.0002175828,0.0002486015,0.00009201056,0.0003474515,0.0001822927,0.0006539493,0.0006137374,0.0005094034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002055973,"about_ca_system_score_gemma":0.0001804927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002960818,"about_ca_topic_score_gemma":0.0003902626,"domain_scores_codex":[0.9997025,0.00006743095,0.00001149298,0.00003895599,0.0001059701,0.00007369402],"domain_scores_gemma":[0.9996487,0.000049747,0.00008897029,0.00003171039,0.00004517381,0.0001356586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003538856,0.0000374208,0.002148976,0.00007428152,0.00001219991,0.0004998776,0.00003435833,0.00008769104,0.991264,0.0002175555,0.0003414994,0.004928376],"study_design_scores_gemma":[0.0002384126,0.003124089,0.06308224,0.00009032164,0.00007335327,0.008153197,0.0005705142,0.002938944,0.8866578,0.0007675428,0.03425619,0.00004734815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843947,0.006555258,0.002871942,0.001323245,0.0003582823,0.00004866688,0.0001729641,0.0001694268,0.00410552],"genre_scores_gemma":[0.9940567,0.0009915036,0.001843727,0.0003335655,0.00008405593,0.00001388347,0.0001145331,0.00002017389,0.002542006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001330887,"threshold_uncertainty_score":0.004452229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01960496585971445,"score_gpt":0.3326300527817841,"score_spread":0.3130250869220697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}