{"id":"W2966997102","doi":"10.1038/s41589-019-0336-0","title":"Mycobacterium tuberculosis releases an antacid that remodels phagosomes","year":2019,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Phagosome; Phagolysosome; Microbiology; Macrophage; Intracellular; Bacteria; Virulence; Biology; Foam cell; Phagocytosis; Chemistry; Pathogen; Cell biology; Gene; Biochemistry; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002902888,0.0002939143,0.0007860704,0.0001454653,0.00003882545,0.00001152594,0.0002809172,0.001525996,0.0008987745],"category_scores_gemma":[0.0008141483,0.000209739,0.0002332554,0.0002093574,0.000221266,0.0001357654,0.0001433726,0.001526552,0.0003834266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001068596,"about_ca_system_score_gemma":0.00008215773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005942757,"about_ca_topic_score_gemma":0.000003910557,"domain_scores_codex":[0.9977068,0.0001911472,0.0003130612,0.0007941812,0.0001882624,0.0008065458],"domain_scores_gemma":[0.9982018,0.0003999057,0.00007546572,0.000695171,0.0001425315,0.0004850568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006506686,0.0001737709,0.123976,0.00007849894,0.0001278869,0.00002010046,0.00002068735,2.716214e-7,0.8645991,0.000951668,0.004423643,0.004977725],"study_design_scores_gemma":[0.003333613,0.001632505,0.06888677,0.0001050333,0.0001727655,0.000784034,0.00007414728,0.0005146635,0.7993206,0.003097906,0.1213578,0.0007201537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844669,0.003182141,0.000009102594,0.007698122,0.0003771955,0.0003746219,0.00005639749,0.0001561942,0.003679325],"genre_scores_gemma":[0.9878615,0.0009610986,0.0008503446,0.008591571,0.0005570559,0.00002274282,0.0008493366,0.00003420847,0.0002721238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1169342,"threshold_uncertainty_score":0.9997702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01960496585971445,"score_gpt":0.3326300527817841,"score_spread":0.3130250869220697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}