{"id":"W2967219560","doi":"10.1016/j.semarthrit.2019.08.002","title":"In IgG4 related disease, elevated IgG2 is an artifact not a biomarker","year":2019,"lang":"en","type":"letter","venue":"Seminars in Arthritis and Rheumatism","topic":"IgG4-Related and Inflammatory Diseases","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Vancouver General Hospital; University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Medicine; Internal medicine; Bone mineral; Rheumatology; Rheumatoid arthritis; Quantitative computed tomography; Medullary cavity; Cortical bone; Biomarker; Prospective cohort study; Bone density; Bone remodeling; Gastroenterology; Urology; Osteoporosis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001778449,0.0006805232,0.0009923342,0.0006933289,0.001850171,0.00207772,0.0009939432,0.02546636,0.004566523],"category_scores_gemma":[0.01690689,0.0004269284,0.0007698687,0.0005502457,0.002469265,0.002350271,0.0008816877,0.01699467,0.00353137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002894999,"about_ca_system_score_gemma":0.001670524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003538631,"about_ca_topic_score_gemma":0.004244162,"domain_scores_codex":[0.9983441,0.0005642596,0.00026188,0.0001879481,0.0003774992,0.000264372],"domain_scores_gemma":[0.9954265,0.002792324,0.0004182461,0.0002033165,0.0006402604,0.0005193553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002697325,0.0001719545,0.01895426,0.0002440107,0.00005936963,0.1621526,0.0006021994,0.0002712116,0.001398689,0.01155392,0.7743379,0.02998406],"study_design_scores_gemma":[0.0004730621,0.0004179319,0.01797296,0.001243948,0.0001354634,0.2878477,0.002498056,0.003316698,0.001579431,0.05773776,0.6265833,0.0001936929],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.004272063,0.001833959,0.0003045387,0.9756301,0.01008565,0.00001229459,0.00003973523,0.00002972321,0.007791898],"genre_scores_gemma":[0.07678109,0.003765408,0.001001013,0.7881539,0.1182858,0.00003241711,0.00007042175,0.00004451158,0.0118653],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02546636,"threshold_uncertainty_score":0.0210048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354564357586332,"score_gpt":0.2520273978649024,"score_spread":0.238481754289039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}