{"id":"W2967245728","doi":"","title":"Engineering Red Blood Cell Progenitors to Achieve Greater Proliferative Potential","year":2015,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Toronto; University of Pennsylvania","keywords":"Progenitor cell; Erythropoietin; Stem cell; Biology; Ectopic expression; Erythropoiesis; Cell biology; Stem cell factor; Bone marrow; Molecular biology; Transcription factor; Doxycycline; Immunology; Transferrin receptor; Cell; Cell culture; Gene; Medicine; Genetics; Internal medicine; Anemia","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002614724,0.0002195703,0.0001935414,0.0001971683,0.0001245944,0.0005394396,0.0001972678,0.000200387,0.0009495685],"category_scores_gemma":[0.0001279713,0.0001357001,0.0001395107,0.0001848781,0.0001337472,0.000153796,0.0003492791,0.0005951815,0.0004711616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205715,"about_ca_system_score_gemma":0.0003037172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002722937,"about_ca_topic_score_gemma":0.000464019,"domain_scores_codex":[0.9998889,0.00001595858,0.00001095873,0.00002207059,0.00004173088,0.00002039478],"domain_scores_gemma":[0.9999121,0.00002080269,0.00001686409,0.00001218308,0.00001932765,0.00001871367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001999539,0.00001277361,0.00009861674,0.00002693205,0.000001655632,0.00004946269,0.00004289466,0.0001292825,0.994955,0.000519246,0.00005646431,0.004087646],"study_design_scores_gemma":[0.000009792856,0.00007289363,0.0005639015,0.00000698132,0.000007230902,0.0002094708,0.00001727504,0.0006287782,0.9862217,0.0001067387,0.0121516,0.000003455038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9238428,0.002730685,0.06220294,0.000236431,0.00008093124,0.000166836,0.0004516824,0.0002354157,0.01005229],"genre_scores_gemma":[0.9270924,0.002485128,0.05039017,0.0001577548,0.00001975724,0.0001238866,0.0006495483,0.0001313571,0.01894995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009495685,"threshold_uncertainty_score":0.00317663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01076809045596025,"score_gpt":0.2338922842788037,"score_spread":0.2231241938228435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}