{"id":"W2967470466","doi":"10.1093/noajnl/vdz014.063","title":"MLTI-04. EVOLUTION OF TREATMENT PARADIGMS FOR PATIENTS WITH ≥1 BRAIN METASTASES FROM PRIMARY NON-SMALL-CELL LUNG CANCER – A SYSTEMATIC REVIEW","year":2019,"lang":"en","type":"review","venue":"Neuro-Oncology Advances","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto","funders":"","keywords":"Medicine; Internal medicine; Lung cancer; Oncology; Randomized controlled trial; Temozolomide; non-small cell lung cancer (NSCLC); Adverse effect; Meta-analysis; Incidence (geometry); Progression-free survival; Clinical trial; Overall survival; Radiation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001239218,0.0006717973,0.005375211,0.0001731418,0.0000860889,0.000008556447,0.0001876913,0.0002049568,0.00004428147],"category_scores_gemma":[0.0001251472,0.0003946604,0.0006394446,0.0002430717,0.00008911428,0.0001378349,0.00003285032,0.0001733941,0.00001130841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002489177,"about_ca_system_score_gemma":0.002845053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001308115,"about_ca_topic_score_gemma":0.00009919138,"domain_scores_codex":[0.9971308,0.00034165,0.001149595,0.0007678592,0.0002462735,0.0003638956],"domain_scores_gemma":[0.9952925,0.001868121,0.001797782,0.0006689542,0.0002399815,0.0001326427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001337826,0.001040451,0.000550299,0.9316216,0.002547731,0.00001861109,0.00007609979,0.00001119542,0.000002975138,0.00001291931,0.0008776642,0.0631067],"study_design_scores_gemma":[0.004701938,0.004477854,0.00003996145,0.3134834,0.08174236,0.00001674791,0.0000165726,0.000008131164,0.000004118676,0.000005493714,0.5951663,0.0003370726],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007759297,0.9755879,0.0002310005,0.0001041756,0.0005435268,0.02042127,0.002692591,0.00003444121,0.0003074974],"genre_scores_gemma":[0.00002802539,0.9844143,0.001361819,0.0004782138,0.0001038785,0.01058041,0.002553151,0.00009293385,0.000387226],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6181381,"threshold_uncertainty_score":0.9998505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0225775951425305,"score_gpt":0.3658963861898324,"score_spread":0.3433187910473019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}