{"id":"W2967585292","doi":"10.1016/j.devcel.2019.07.026","title":"P Granules Protect RNA Interference Genes from Silencing by piRNAs","year":2019,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Canadian Institutes of Health Research; Johns Hopkins University; School of Medicine, Johns Hopkins University; National Institutes of Health","keywords":"Piwi-interacting RNA; Argonaute; Biology; Gene silencing; RasiRNA; RNA interference; RNA-induced silencing complex; Trans-acting siRNA; RNA; Cell biology; Small RNA; RNA silencing; Genetics; Germline; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008243827,0.0002140817,0.0001533506,0.00002712555,0.0000736582,0.00004390939,0.0003088804,0.0001299801,0.0002344452],"category_scores_gemma":[0.000007748256,0.0002133164,0.00005500936,0.00004326927,0.00004294689,0.000005324704,0.0002079642,0.0001032158,0.0003234144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003219368,"about_ca_system_score_gemma":0.00008254655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001805099,"about_ca_topic_score_gemma":0.00005167173,"domain_scores_codex":[0.9988772,0.00003469013,0.0002105443,0.0004565422,0.0001462729,0.0002747909],"domain_scores_gemma":[0.9995711,0.000007536128,0.00007379664,0.0002279132,0.00003603843,0.0000835669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001973306,0.00003927372,0.007445648,0.00002133682,0.00002188425,0.000001473226,0.0005155288,0.00001269922,0.9882708,0.000001232873,0.001360429,0.002289935],"study_design_scores_gemma":[0.0003861884,0.0001057794,0.001913658,0.00001710036,0.000007684841,0.000003880142,0.0003687704,0.00003857323,0.9861655,0.0000486018,0.01062364,0.0003206883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920338,0.001183194,0.003301301,0.00002712263,0.0002785551,0.000276897,0.00003913086,0.00002182091,0.002838192],"genre_scores_gemma":[0.9909987,0.0002088391,0.005847656,0.0002979167,0.00007895628,0.0000181105,0.0002931929,0.0000325565,0.002224024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009263209,"threshold_uncertainty_score":0.8698788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006061670222802971,"score_gpt":0.18582376567705,"score_spread":0.179762095454247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}