{"id":"W2967585292","doi":"10.1016/j.devcel.2019.07.026","title":"P Granules Protect RNA Interference Genes from Silencing by piRNAs","year":2019,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Canadian Institutes of Health Research; Johns Hopkins University; School of Medicine, Johns Hopkins University; National Institutes of Health","keywords":"Piwi-interacting RNA; Argonaute; Biology; Gene silencing; RasiRNA; RNA interference; RNA-induced silencing complex; Trans-acting siRNA; RNA; Cell biology; Small RNA; RNA silencing; Genetics; Germline; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444306,0.0003785914,0.0003023104,0.0002773831,0.0002381014,0.0005198063,0.0002797919,0.0004510437,0.0013441],"category_scores_gemma":[0.0004021479,0.0001961748,0.0003201847,0.00009096637,0.0003966742,0.0006244287,0.0005193541,0.0006597904,0.0006258166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666766,"about_ca_system_score_gemma":0.0001808197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001923448,"about_ca_topic_score_gemma":0.0002395409,"domain_scores_codex":[0.9998466,0.00002442935,0.00001356295,0.0000471887,0.00003712711,0.00003107836],"domain_scores_gemma":[0.9996362,0.000077198,0.00009564582,0.00008594371,0.00003788499,0.0000670438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001572391,0.000008640196,0.0001777374,0.00001815093,0.000004694969,0.000086529,0.00001688181,0.00002919859,0.9971023,0.0006446905,0.00008188238,0.001672138],"study_design_scores_gemma":[0.00002178687,0.0001699212,0.002722892,0.000005768213,0.00001074306,0.0003581702,0.00002773634,0.0005665492,0.9930248,0.0009226312,0.002162377,0.000006581836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714153,0.002105739,0.02138105,0.0003927886,0.0001304751,0.00002729637,0.0003616001,0.0007194309,0.00346624],"genre_scores_gemma":[0.9925724,0.0003715586,0.003257814,0.0001100138,0.00003429021,0.00002252675,0.0002937013,0.0001243237,0.00321333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013441,"threshold_uncertainty_score":0.004496515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006061670222802971,"score_gpt":0.18582376567705,"score_spread":0.179762095454247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}